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NCT01627067 · ClinicalTrials.gov registry record · Phase 2

Exemestane-RAD001-Metformin

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
Phase 2
Development phase
23
Enrollment target

NCT01627067: Clinical Trial Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT01627067 is a Phase 2 study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 23 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01627067, a Phase 2 study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
23 participants
Enrollment target

Study Summary

The goal of this clinical research study is to learn if exemestane and everolimus combined with metformin can help to control breast cancer in patients who are obese or overweight and post-menopausal with hormone-receptor-positive breast cancer that has spread to other parts of the body. Exemestane is designed to decrease the ability of estrogen to help cancer cells grow. This could cause the cancer cells to die. Metformin is commonly used to control blood sugar levels in patients with diabetes. It is designed to lower insulin levels, which may slow or stop the growth of breast cancer cells. Everolimus is designed to block cells from dividing. This may cause cancer cells to die. Everolimus may also stop the growth of new blood vessels that help tumors grow.

Interventions

  • DRUG Exemestane
  • DRUG Everolimus
  • DRUG Metformin

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2012-09
Est. Completion 2019-02-01
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT01627067

The ClinicalTrials.gov registry entry for NCT01627067 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 23 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Exemestane is the first listed.

NCT01627067 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01627067 about?

NCT01627067 is a clinical study titled "Exemestane-RAD001-Metformin". The goal of this clinical research study is to learn if exemestane and everolimus combined with metformin can help to control breast cancer in patients who are obese or overweight and post-menopausal with hormone-receptor-positive breast cancer that has spread to other parts of the body. Exemestane...

What is the current status of trial NCT01627067?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2012-09. Estimated completion is 2019-02-01.

What interventions are being tested in trial NCT01627067?

The interventions under investigation include: Exemestane (DRUG), Everolimus (DRUG), Metformin (DRUG).

Who is sponsoring clinical trial NCT01627067?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.