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NCT00587860 · ClinicalTrials.gov registry record · Phase 2
A Placebo-Controlled Trial of St. John's Wort for Irritable Bowel Syndrome
A Phase 2 study of Irritable Bowel Syndrome, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT00587860: Completed Phase 2 study of Irritable Bowel Syndrome, sponsored by Mayo Clinic.
NCT00587860 is a Phase 2 study of Irritable Bowel Syndrome that has completed, run by Mayo Clinic. The registered enrollment target is 70 participants, below the 143-participant average among 47 other Irritable Bowel Syndrome trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00587860, a Phase 2 study of Irritable Bowel Syndrome, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being done to see if St. John's wort helps people with irritable bowel syndrome, otherwise known as "IBS". St. John's wort is a herbal supplement derived from the St. John's wort plant. It has been shown to be helpful in several medical conditions such as depression as well as other pain syndromes.
Primary Outcome
The primary end point was the overall self-reported BSS after 12 weeks of therapy for all randomized participants to assess for differences between treatment groups at the end of the treatment period (12 weeks). The BSS is a 100-mm visual analog scale for the different symptoms of IBS (pain/discomfort, constipation, diarrhea, and overall severity). Symptoms on the BSS can range from 0 = no pain to 100 = extreme pain.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG St. John's wort
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2006-02 |
| Est. Completion | 2008-03 |
| Phase | Phase 2 |
What the finished NCT00587860 record still lists
NCT00587860 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 143-participant average among 47 other Irritable Bowel Syndrome trials with a reported enrollment target (51% lower).
The record links to 1 condition, with Irritable Bowel Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00587860 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT00587860 about?
NCT00587860 is a clinical study titled "A Placebo-Controlled Trial of St. John's Wort for Irritable Bowel Syndrome". This study is being done to see if St. John's wort helps people with irritable bowel syndrome, otherwise known as "IBS". St. John's wort is a herbal supplement derived from the St. John's wort plant. It has been shown to be helpful in several medical conditions such as depression as well as other pa...
What is the current status of trial NCT00587860?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2006-02. Estimated completion is 2008-03.
What conditions does trial NCT00587860 study?
This clinical trial studies the following conditions: Irritable Bowel Syndrome.
What interventions are being tested in trial NCT00587860?
The interventions under investigation include: Placebo (DRUG), St. John's wort (DRUG).
Who is sponsoring clinical trial NCT00587860?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00587860 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Irritable Bowel Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00587860's enrollment target sits among peer trials
70 28th of 47 higher than 19 of 47 other Irritable Bowel Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Irritable Bowel Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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