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NCT00573911 · ClinicalTrials.gov registry record · Phase 1
Acid Reflux and Stromal Fibroblasts in Barrett's Esophagus
A Phase 1 study of Barrett's Esophagus and GERD, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT00573911: Completed Phase 1 study of Barrett's Esophagus and GERD, sponsored by Mayo Clinic.
NCT00573911 is a Phase 1 study of Barrett's Esophagus and GERD that has completed, run by Mayo Clinic. The registered enrollment target is 16 participants, below the 524-participant average among 22 other Barrett's Esophagus trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00573911, a Phase 1 study of Barrett's Esophagus and GERD, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with Barrett's Esophagus are known to have excessive distal esophageal acid exposure comparable to patients with erosive esophagitis. A significant proportion of patients with BE who are not symptomatic on treatment continue to have persistent acid reflux. High dose esomeprazole is able to control acid reflux in patients with BE. The effect of acid reflux on Barrett's esophagus stroma is currently unknown. It is our hypothesis that stromal fibroblast activation in Barrett's esophagus is influenced by acid reflux. The specific aim of this proposal will be: To assess the association between acid reflux and subepithelial fibroblasts in Barrett's esophagus.
Conditions Studied
Interventions
- PROCEDURE Endoscopy and pH study
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2007-08 |
| Est. Completion | 2011-01 |
| Phase | Phase 1 |
What the finished NCT00573911 record still lists
NCT00573911 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 524-participant average among 22 other Barrett's Esophagus trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Barrett's Esophagus appearing as the primary indexed condition, and to 1 intervention - of which Endoscopy and pH study is the first listed.
NCT00573911 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT00573911 about?
NCT00573911 is a clinical study titled "Acid Reflux and Stromal Fibroblasts in Barrett's Esophagus". Patients with Barrett's Esophagus are known to have excessive distal esophageal acid exposure comparable to patients with erosive esophagitis. A significant proportion of patients with BE who are not symptomatic on treatment continue to have persistent acid reflux. High dose esomeprazole is able to ...
What is the current status of trial NCT00573911?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2007-08. Estimated completion is 2011-01.
What conditions does trial NCT00573911 study?
This clinical trial studies the following conditions: Barrett's Esophagus, GERD.
What interventions are being tested in trial NCT00573911?
The interventions under investigation include: Endoscopy and pH study (PROCEDURE).
Who is sponsoring clinical trial NCT00573911?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00573911 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Barrett's Esophagus
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00573911's enrollment target sits among peer trials
16 21st of 22 higher than 2 of 22 other Barrett's Esophagus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Barrett's Esophagus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Pilot Study for TCE Imaging of the Esophagus Using an OFDI Capsule With a Compact Imaging System
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TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)
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RECRUITING · NA
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