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NCT05740501 · ClinicalTrials.gov registry record

Pharmacokinetic Profiling of Pembrolizumab and Nivolumab in Patients With Melanoma and/or Non-Small Cell Lung Cancer

A clinical trial of Melanoma and Lung Non-Small Cell Carcinoma, sponsored by Mayo Clinic.

Completed
Registry status
13
Enrollment target
1
Study location

NCT05740501 is a study of Melanoma and Lung Non-Small Cell Carcinoma that has completed, run by Mayo Clinic. The registered enrollment target is 13 participants, below the 706-participant average among 266 other Melanoma trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05740501, a study of Melanoma and Lung Non-Small Cell Carcinoma, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
13 participants
Enrollment target
1
Study location

Study Summary

This early phase I study collects blood samples and monitors the levels of pembrolizumab and nivolumab as they move through the body in patients with melanoma and/or non-small cell lung cancer. Pembrolizumab and nivolumab are a monoclonal antibodies that may interfere with the ability of cancer cells to grow and spread. Studying samples of blood in the laboratory from patients receiving pembrolizumab and nivolumab may help doctors learn more about the effects of pembrolizumab and nivolumab on cells. It may also help doctors understand how well patients respond to treatment. Information from this study may be used in the future to guide physicians to make dosage adjustments based on serum concentrations of drug to minimize adverse side effects and maximize the effect of the drug.

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Questionnaire Administration
  • OTHER Electronic Health Record Review

Study Locations (1)

Minnesota

  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2017-04-26
Est. Completion 2020-01-03

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT05740501

The ClinicalTrials.gov registry entry for NCT05740501 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 706-participant average among 266 other Melanoma trials with a reported enrollment target (98% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Melanoma appearing as the primary indexed condition, and to 3 interventions - of which Biospecimen Collection is the first listed.

NCT05740501 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT05740501 about?

NCT05740501 is a clinical study titled "Pharmacokinetic Profiling of Pembrolizumab and Nivolumab in Patients With Melanoma and/or Non-Small Cell Lung Cancer". This early phase I study collects blood samples and monitors the levels of pembrolizumab and nivolumab as they move through the body in patients with melanoma and/or non-small cell lung cancer. Pembrolizumab and nivolumab are a monoclonal antibodies that may interfere with the ability of cancer cell...

What is the current status of trial NCT05740501?

This trial is currently completed. The enrollment target is 13 participants. The study started on 2017-04-26. Estimated completion is 2020-01-03.

What conditions does trial NCT05740501 study?

This clinical trial studies the following conditions: Melanoma, Lung Non-Small Cell Carcinoma.

What interventions are being tested in trial NCT05740501?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Questionnaire Administration (OTHER), Electronic Health Record Review (OTHER).

Who is sponsoring clinical trial NCT05740501?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05740501 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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