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NCT03211117 · ClinicalTrials.gov registry record · Phase 2

Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer

A Phase 2 study, sponsored by Mayo Clinic.

Completed
Registry status
Phase 2
Development phase
3
Enrollment target

NCT03211117: Completed Phase 2 study, sponsored by Mayo Clinic.

NCT03211117 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 3 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03211117, a Phase 2 study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 2
Development phase
3 participants
Enrollment target

Study Summary

This phase II trial studies how well pembrolizumab, chemotherapy, and radiation therapy work with or without surgery in treating patients with anaplastic thyroid cancer. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as docetaxel and doxorubicin hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-energy x-rays to kill tumor cells and shrink tumors. Giving pembrolizumab, chemotherapy, and radiation therapy with or without surgery may kill more tumor cells and work better in treating patients with anaplastic thyroid cancer.

Interventions

  • BIOLOGICAL Pembrolizumab
  • DRUG Docetaxel
  • OTHER Laboratory Biomarker Analysis
  • DRUG Doxorubicin Hydrochloride
  • RADIATION Intensity-Modulated Radiation Therapy

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2017-08-14
Est. Completion 2019-03-28
Phase Phase 2

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT03211117

The ClinicalTrials.gov registry entry for NCT03211117 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Pembrolizumab is the first listed.

NCT03211117 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03211117 about?

NCT03211117 is a clinical study titled "Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer". This phase II trial studies how well pembrolizumab, chemotherapy, and radiation therapy work with or without surgery in treating patients with anaplastic thyroid cancer. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of tumor cells to grow and spread. Drugs used in chem...

What is the current status of trial NCT03211117?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 3 participants. The study started on 2017-08-14. Estimated completion is 2019-03-28.

What interventions are being tested in trial NCT03211117?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Docetaxel (DRUG), Laboratory Biomarker Analysis (OTHER), Doxorubicin Hydrochloride (DRUG), Intensity-Modulated Radiation Therapy (RADIATION).

Who is sponsoring clinical trial NCT03211117?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.