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NCT04417998 · ClinicalTrials.gov registry record · Phase 4

Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction

A Phase 4 study, sponsored by Mayo Clinic.

Completed
Registry status
Phase 4
Development phase
80
Enrollment target

NCT04417998: Completed Phase 4 study, sponsored by Mayo Clinic.

NCT04417998 is a Phase 4 study that has completed, run by Mayo Clinic. The registered enrollment target is 80 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT04417998, a Phase 4 study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 4
Development phase
80 participants
Enrollment target

Study Summary

The purpose of this study is to assess the effectiveness of new software available on a new PET/CT scanner in the Molecular Imaging Research PET/CT Facility. Further, the study aims to evaluate the data acquisition and image processing workflow.

Primary Outcome

Confirm that motion-corrected reconstructed images acquired when the subject was moving provides similar image quality to the baseline reference reconstructed images acquired when the subject was instructed to remain still. For each subject compute the cumulative absolute relative difference (ARD) histogram in standard uptake values in grey matter voxels in images with and without motion correction versus a reference image for which the subject was stationary, then calculate the percentage of vo

Interventions

  • DRUG 18F-FDG
  • DRUG 18F-AV1451
  • DEVICE Siemens E7 Reconstruction Tool

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2020-06-03
Est. Completion 2023-12-20
Phase Phase 4
Mayo Clinic

2,844 total trials

What the finished NCT04417998 record still lists

NCT04417998 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (85% lower).

The record links to 0 conditions, and to 3 interventions - of which 18F-FDG is the first listed.

NCT04417998 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04417998 about?

NCT04417998 is a clinical study titled "Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction". The purpose of this study is to assess the effectiveness of new software available on a new PET/CT scanner in the Molecular Imaging Research PET/CT Facility. Further, the study aims to evaluate the data acquisition and image processing workflow.

What is the current status of trial NCT04417998?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 80 participants. The study started on 2020-06-03. Estimated completion is 2023-12-20.

What interventions are being tested in trial NCT04417998?

The interventions under investigation include: 18F-FDG (DRUG), 18F-AV1451 (DRUG), Siemens E7 Reconstruction Tool (DEVICE).

Who is sponsoring clinical trial NCT04417998?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04417998's enrollment target sits among peer trials

80 946th of 2000 higher than 1,021 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04417998, the US trial registry maintained by the National Library of Medicine. NCT04417998 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.