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NCT07104812 · ClinicalTrials.gov registry record · Phase 2
Impact of 1 mg Osilodrostat Therapy on Mild Autonomous Cortisol Secretion (MACS)
A Phase 2 study of Mild Autonomous Cortisol Secretion and Autonomous Cortisol Secretion (ACS), sponsored by Mayo Clinic.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT07104812: Recruiting Phase 2 study of Mild Autonomous Cortisol Secretion and Autonomous Cortisol Secretion (ACS), sponsored by Mayo Clinic.
NCT07104812 is a Phase 2 study of Mild Autonomous Cortisol Secretion and Autonomous Cortisol Secretion (ACS) that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 15 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07104812, a Phase 2 study of Mild Autonomous Cortisol Secretion and Autonomous Cortisol Secretion (ACS), is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to evaluate the safety and tolerability of 1 mg osilodrostat therapy in patients with mild autonomous cortisol secretion (MACS), and to determine the impact on 24h urine steroid metabolome and circadian cortisol/cortisone concentrations
Conditions Studied
Interventions
- DRUG Osilodrostat 1 MG
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2026-01-14 |
| Est. Completion | 2027-01 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07104812
The ClinicalTrials.gov registry entry for NCT07104812 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Mild Autonomous Cortisol Secretion appearing as the primary indexed condition, and to 1 intervention - of which Osilodrostat 1 MG is the first listed.
NCT07104812 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT07104812 about?
NCT07104812 is a clinical study titled "Impact of 1 mg Osilodrostat Therapy on Mild Autonomous Cortisol Secretion (MACS)". The purpose of this study is to evaluate the safety and tolerability of 1 mg osilodrostat therapy in patients with mild autonomous cortisol secretion (MACS), and to determine the impact on 24h urine steroid metabolome and circadian cortisol/cortisone concentrations
What is the current status of trial NCT07104812?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2026-01-14. Estimated completion is 2027-01.
What conditions does trial NCT07104812 study?
This clinical trial studies the following conditions: Mild Autonomous Cortisol Secretion, Autonomous Cortisol Secretion (ACS).
What interventions are being tested in trial NCT07104812?
The interventions under investigation include: Osilodrostat 1 MG (DRUG).
Who is sponsoring clinical trial NCT07104812?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07104812 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Mild Autonomous Cortisol Secretion
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Autonomous Cortisol Secretion (ACS)
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