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NCT06646406 · ClinicalTrials.gov registry record · NA

Evaluation of a Multilevel Intervention on Adult COVID-19 and Influenza Vaccination Rate

A NA study, sponsored by Mayo Clinic.

Completed
Registry status
NA
Development phase
114,165
Enrollment target

NCT06646406: Completed NA study, sponsored by Mayo Clinic.

NCT06646406 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 114,165 participants, above the 1,402-participant average among 58,714 other NA trials with a reported enrollment target (8043% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06646406, a NA study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
NA
Development phase
114,165 participants
Enrollment target

Study Summary

The study will test two tactics to improve uptake of two vaccines in adults. The vaccines prevent COVID-19 and influenza. Both are common and harmful. Most adults do not get either vaccine. This is despite strong recommendations that all adults get both vaccines. The study will involve adult patients at eight Mayo Clinic primary care practices in Rochester and Kasson. The study will test the two tactics together. Four clinics will get the two tactics. The other four clinics will not. The study will randomly assign the two tactics to the clinics. One tactic is to send a letter by US mail to the patient. The letter will state strong recommendations on getting both vaccines now. It will tell patients how to get the vaccines now. The second tactic is to send monthly emails to clinicians. It will remind them to use every visit to vaccinate patients against COVID-19 and influenza. The study will compare the uptake of the two vaccines after six months in the clinics with and without the two tactics.

Primary Outcome

Rates of at least one dose of single licensed 2024-2025 COVID-19 vaccine among adult patients at eight Mayo Clinic primary care practices

Interventions

  • BEHAVIORAL Patient letter and clinician communication

Trial Details

FieldValue
Enrollment Target 114,165 participants
Start Date 2024-10-21
Est. Completion 2025-04-30
Phase NA
Mayo Clinic

2,844 total trials

What the finished NCT06646406 record still lists

NCT06646406 is an interventional study that assigns participants to a tested intervention. Its 114,165 participants enrollment target places it among the larger protocols in the corpus, above the 1,402-participant average among 58,714 other NA trials with a reported enrollment target (8043% higher).

The record links to 0 conditions, and to 1 intervention - of which Patient letter and clinician communication is the first listed.

NCT06646406 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06646406 about?

NCT06646406 is a clinical study titled "Evaluation of a Multilevel Intervention on Adult COVID-19 and Influenza Vaccination Rate". The study will test two tactics to improve uptake of two vaccines in adults. The vaccines prevent COVID-19 and influenza. Both are common and harmful. Most adults do not get either vaccine. This is despite strong recommendations that all adults get both vaccines. The study will involve adult patien...

What is the current status of trial NCT06646406?

This trial is currently completed. It is a NA study. The enrollment target is 114,165 participants. The study started on 2024-10-21. Estimated completion is 2025-04-30.

What interventions are being tested in trial NCT06646406?

The interventions under investigation include: Patient letter and clinician communication (BEHAVIORAL).

Who is sponsoring clinical trial NCT06646406?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06646406's enrollment target sits among peer trials

114,165 2nd of 2000 the highest of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06646406, the US trial registry maintained by the National Library of Medicine. NCT06646406 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.