Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 40 of 41

COMPLETED Phase 4

Folate Supplementation in Schizophrenia

NCT00249288

COMPLETED Phase 4

Strattera Treatment in Adults With Attention Deficit Hyperactivity Disorder Not Otherwise Specified (ADHD NOS)

NCT00181766

COMPLETED Phase 4

Concerta Treatment in Adults With ADHD NOS

NCT00181740

COMPLETED NA

A Medication Trial Combined With Behavior Therapy for Individuals With Obsessive-compulsive Disorder

NCT00126282

COMPLETED NA

Pathogenesis of Chronic Sinusitis in Relationship to Tobacco Smoke Exposure

NCT01179139

COMPLETED

Inflammation and the Host Response to Injury (Trauma)

NCT00257231

COMPLETED Phase 4

Prevention of Cigarette Smoking in Attention Deficit Hyperactivity Disorder (ADHD) Youth With Concerta

NCT00181714

COMPLETED Phase 2

Iressa (ZD1839) Plus Anastrozole (Arimidex) in Patients With Ovarian Cancer

NCT00181688

COMPLETED

Internet-Based Cervical Cytology Screening Program

NCT00658190

COMPLETED NA

Defining Central Circuits of Pain

NCT00112333

COMPLETED Phase 2

Zoledronic Acid to Prevent Bone Loss During Androgen Deprivation Therapy for Prostate Cancer

NCT00181584

COMPLETED Phase 4

Effectiveness of Pramipexole for Treatment-Resistant Depression

NCT00231959

COMPLETED NA

Partial Breast Irradiation (PBI) for Selected Patients With Early Invasive or Non-Invasive Breast Cancer

NCT00694577

COMPLETED Phase 4

Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment

NCT00337350

COMPLETED NA

A Prospective Randomized Trial of Static-Progressive Versus Dynamic Splinting for Post-Traumatic Elbow Stiffness

NCT01241916

COMPLETED Phase 4

Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram

NCT00183677

COMPLETED Phase 4

Naturalistic Substitution of Concerta in Adult Subject With ADHD Receiving Immediate Release Methylphenidate

NCT00302406

COMPLETED NA

Culturally Sensitive Collaborative Treatment for Depressed Chinese Americans

NCT00227929

COMPLETED Phase 2

Effects of Anorexia Nervosa on Bone Mass in Adolescents

NCT00088153

COMPLETED Phase 1

VELCADE in Combination With Idarubicin and Cytosine Arabinoside in Patients With Acute Myelogenous Leukemia

NCT00505700

COMPLETED Phase 4

A Double-Blind Comparison of Concerta and Placebo in Adults With Attention Deficit Hyperactivity Disorder

NCT00181571

COMPLETED Phase 3

The Combination of Aripiprazole and Antidepressants in Psychotic Major Depression

NCT00556140

COMPLETED Phase 2

Bone Loss in Women With Anorexia Nervosa

NCT00089843

COMPLETED NA

Study of Lifestyle Modification in HIV Lipodystrophy

NCT00111358

COMPLETED Phase 1

Phase I Study of Sequential Cord Blood Transplants

NCT00299767

COMPLETED NA

Corticosteroid Injection for Common Upper Extremity Problems

NCT00438672

COMPLETED Phase 2

Gefitinib in Treating Patients With Locally Advanced or Metastatic Thyroid Cancer That Did Not Respond to Iodine Therapy

NCT00095836

TERMINATED

Screening Protocol for Children and Adolescents With Attention Deficit Hyperactivity Disorder

NCT00592436

COMPLETED NA

Drug Therapy to Treat Minor Depression

NCT00048815

COMPLETED Phase 4

Risperidone Augmentation in Patients With Schizophrenia

NCT00289861

COMPLETED Phase 4

Aripiprazole for the Treatment of Mania in Children and Adolescents With Bipolar Disorder

NCT00181779

COMPLETED NA

Motivational Interviewing Compared to Psychoeducation for Smoking Precontemplators With SMI

NCT01982617

COMPLETED NA

Modified Directly Observed Therapy for Improving Antiretroviral Therapy Adherence in People With HIV

NCT00339092

COMPLETED Phase 1

Trial of Paroxetine-CR for the Treatment of Patients With Post Traumatic Stress Disorder Remaining Symptomatic After Initial Exposure Therapy

NCT00121888

COMPLETED

Spectroscopy in Children and Adolescents With Bipolar Disorder

NCT00181831

COMPLETED Phase 4

A Double-Blind Comparison of Galantamine HBr and Placebo in Adults With Attention Deficit Hyperactivity Disorder

NCT00181675

COMPLETED Phase 4

A Study of Sertraline to Prevent PTSD

NCT00182078

COMPLETED NA

Secondary Analysis of Gut Hormones and Inflammatory Cytokines in Fasting Subjects

NCT01257841

COMPLETED NA

Study of Home-Based Resistance and Strength Training in HIV-Infected Women

NCT00111332

COMPLETED

Prospective Study of Insulin Resistance and Cardiovascular Disease Risk During Androgen Deprivation Therapy for Prostate Cancer

NCT00455624

TERMINATED Phase 2

Non-Myeloablative HLA-Mismatched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies

NCT00113646

COMPLETED Phase 4

Escitalopram for the Treatment of Obsessive Compulsive Disorder (OCD)

NCT00116532

COMPLETED Phase 4

Escitalopram for the Treatment of Self-Injurious Skin Picking

NCT00115011

COMPLETED Phase 4

Concerta in the Treatment of ADHD in Youth and Adults With Bipolar Disorder

NCT00181987

COMPLETED Phase 2

ET 743 (Yondelis) in Men With Advanced Prostate Cancer

NCT00147212

COMPLETED NA

Proton Beam Radiation Therapy in Treating Young Patients Who Have Undergone Biopsy or Surgery for Medulloblastoma or Pineoblastoma

NCT00105560

COMPLETED Phase 2

The Safety and Efficacy of Recombinant Human Prolactin

NCT00438490

COMPLETED Phase 4

Ziprasidone for the Treatment of Mania in Children and Adolescents With Bipolar Disorder

NCT00181922

COMPLETED NA

Growth Hormone Administration and Its Effects on Cardiovascular Risk Factors in Growth Hormone Deficient Women

NCT00136032

COMPLETED Phase 3

Study of Sildenafil in Patient With Heart Failure.

NCT00309816

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Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.