Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 41 of 41

COMPLETED Phase 2

Atrasentan and Zometa for Men With Prostate Cancer Metastatic to Bone

NCT00181558

COMPLETED NA

Biochemical Brain Changes Correlated With The Antidepressant Effect Of Thyroid Hormones

NCT00562367

COMPLETED NA

Androgen Replacement Therapy in Women With Hypopituitarism

NCT00027430

COMPLETED Phase 1

Cognitive Behavioral Therapy for Adult Attention Deficit Hyperactivity Disorder

NCT00050050

COMPLETED Phase 3

Efficacy of Proactive Telephone Counseling for Pregnant Smokers Enrolled in a Managed Care Organization

NCT00181909

COMPLETED Phase 1

Combined Bone Marrow Transplantation (BMT) and Renal Transplant for Multiple Myeloma (MM) With End Stage Renal Disease (ESRD)

NCT00854139

COMPLETED

The Partners Genetics Collaborative Study of Schizophrenia

NCT00319904

COMPLETED Phase 4

Risperidone Versus Olanzapine for Mania in Preschool Children 4 to 6 Years of Age With Bipolar Disorder

NCT00181935

COMPLETED Phase 2

Antidepressant Medication Plus Directly Observed Therapy for Improving Adherence to Antiretroviral Therapy

NCT00338767

COMPLETED Phase 2

Phase II Study of Modified Triple Doublet Therapy in Women With Newly Diagnosed Mullerian Carcinoma

NCT00157560

COMPLETED Phase 1

Postmenopausal Women Estrogen and Progesterone Infusion

NCT00455741

COMPLETED Phase 3

Rosiglitazone (Avandia) vs. Placebo for Androgen Dependent Prostate Cancer

NCT00182052

TERMINATED NA

Determining the Safety and Effectiveness of Olanzapine in Children and Adolescents

NCT00183612

COMPLETED

Multicenter Benchmarking of Functional and Psychosocial Outcomes of Pediatric Burn Survivors

NCT00239668

COMPLETED NA

Efficacy of a Fibrin Sealant in Burn Surgery

NCT00181974

COMPLETED Phase 2

Neoadjuvant Chemotherapy Using Doxorubicin and Paclitaxel in Treating Women With Large Breast Cancer

NCT00096291

COMPLETED Phase 4

Sertraline and Habit Reversal in the Treatment of Patients With Trichotillomania

NCT00118014

COMPLETED Phase 4

Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease

NCT00181818

COMPLETED Phase 3

Effects of Parathyroid Hormone in Men With Osteoporosis

NCT00000427

COMPLETED Phase 2

Alendronate and/or Parathyroid Hormone for Osteoporosis

NCT00000400

COMPLETED Phase 1

Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine

NCT00592748

COMPLETED Phase 1

High-Dose Proton/Photon RT + Surgery of Sarcomas of the Thoracic, Lumbar Spine/Sacrum

NCT00592345

COMPLETED Phase 3

Proton/Photon Rt - Benign Meningiomas(P92-13)

NCT02947984

COMPLETED Phase 2

Therapies for Treatment-Resistant Panic Disorder Symptoms

NCT00118417

COMPLETED Phase 1

Studying the Effects of 7 Days of Gonadotropin Releasing Hormone (GnRH) Treatment in Men With Hypogonadism

NCT00493961

COMPLETED

Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders

NCT00494169

COMPLETED NA

Early Intervention for Children at Risk for Anxiety

NCT00865306

COMPLETED Phase 1

Paclitaxel and Radiation Therapy Plus Chemoprotection With Amifostine in Treating Patients With Stage III or Stage IV Head and Neck Cancer

NCT00003193

COMPLETED Phase 1

Treatment of T1N0 Invasive Breast Carcinoma by Local Excision Implant

NCT00977275

TERMINATED

Psychometric Study of Outcomes Instruments

NCT00253292

COMPLETED Phase 1

Examination of Idiopathic Hypogonadotropic Hypogonadism (IHH)and Kallmann Syndrome (KS)

NCT00392756

COMPLETED NA

Galantamine-CR and Cognitive Dysfunction in Bipolar Disorder

NCT00181636

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Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.