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NCT00181675 · ClinicalTrials.gov registry record · Phase 4

A Double-Blind Comparison of Galantamine HBr and Placebo in Adults With Attention Deficit Hyperactivity Disorder

A Phase 4 study, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 4
Development phase
40
Enrollment target

NCT00181675: Completed Phase 4 study, sponsored by Massachusetts General Hospital.

NCT00181675 is a Phase 4 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00181675, a Phase 4 study, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 4
Development phase
40 participants
Enrollment target

Study Summary

This will be a double-blind, placebo-controlled, study using daily doses of up to 24 mg/ day Galantamine HBr in the treatment of adults who meet DSM-IV criteria for childhood-onset ADHD. Specific hypotheses are as follows: Hypothesis 1: ADHD symptomatology in adults with DSM-IV ADHD will be responsive to acute Galantamine HBr treatment. Hypothesis 2: Galantamine HBr -associated improvement in ADHD symptomatology in adults will translate into improved functional capacities (neuropsychological, social, and occupational) as well as an increased quality of life throughout acute treatment. Hypothesis 3: Galantamine HBr treatment will be safe and well tolerated as reflected by a low drop out rate and absence of major differences from placebo.

Interventions

  • DRUG galantamine HBr

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2002-12
Est. Completion 2003-09
Phase Phase 4
Massachusetts General Hospital

2,032 total trials

What the finished NCT00181675 record still lists

NCT00181675 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which galantamine HBr is the first listed.

NCT00181675 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00181675 about?

NCT00181675 is a clinical study titled "A Double-Blind Comparison of Galantamine HBr and Placebo in Adults With Attention Deficit Hyperactivity Disorder". This will be a double-blind, placebo-controlled, study using daily doses of up to 24 mg/ day Galantamine HBr in the treatment of adults who meet DSM-IV criteria for childhood-onset ADHD. Specific hypotheses are as follows: Hypothesis 1: ADHD symptomatology in adults with DSM-IV ADHD will be respons...

What is the current status of trial NCT00181675?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2002-12. Estimated completion is 2003-09.

What interventions are being tested in trial NCT00181675?

The interventions under investigation include: galantamine HBr (DRUG).

Who is sponsoring clinical trial NCT00181675?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00181675's enrollment target sits among peer trials

40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00181675, the US trial registry maintained by the National Library of Medicine. NCT00181675 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.