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NCT00183677 · ClinicalTrials.gov registry record · Phase 4
Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram
A Phase 4 study of Depression, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Phase 4
- Development phase
- 97
- Enrollment target
- 1
- Study location
NCT00183677: Completed Phase 4 study of Depression, sponsored by Massachusetts General Hospital.
NCT00183677 is a Phase 4 study of Depression that has completed, run by Massachusetts General Hospital. The registered enrollment target is 97 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00183677, a Phase 4 study of Depression, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 97 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will evaluate changes in brain energy metabolism due to treatment with escitalopram in people with major depressive disorder.
Primary Outcome
The Hamilton Depression Rating Scale, 17 items (HAMD-17, range 0-52) was used to measure changes in depression severity from baseline to endpoint. Clinical Responder status was defined as \> 50% improvement (i.e., reduction) in HAMD-17 score from baseline to endpoint. Clinical Remission status was defined as HAMD-17 score \< 8 at endpoint (week 12 visit).
Conditions Studied
Interventions
- DRUG Escitalopram
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 97 participants |
| Start Date | 2003-07 |
| Est. Completion | 2009-06 |
| Phase | Phase 4 |
What the finished NCT00183677 record still lists
NCT00183677 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 97 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (88% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Escitalopram is the first listed.
NCT00183677 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00183677 about?
NCT00183677 is a clinical study titled "Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram". This study will evaluate changes in brain energy metabolism due to treatment with escitalopram in people with major depressive disorder.
What is the current status of trial NCT00183677?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 97 participants. The study started on 2003-07. Estimated completion is 2009-06.
What conditions does trial NCT00183677 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT00183677?
The interventions under investigation include: Escitalopram (DRUG).
Who is sponsoring clinical trial NCT00183677?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00183677 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00183677's enrollment target sits among peer trials
97 351st of 679 higher than 328 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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