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NCT00089843 · ClinicalTrials.gov registry record · Phase 2

Bone Loss in Women With Anorexia Nervosa

A Phase 2 study, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 2
Development phase
77
Enrollment target

NCT00089843: Completed Phase 2 study, sponsored by Massachusetts General Hospital.

NCT00089843 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 77 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (42% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00089843, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 2
Development phase
77 participants
Enrollment target

Study Summary

Women with Anorexia Nervosa have been found to have low bone density. The study will determine whether administration of low doses of a natural hormone, testosterone and/or risedronate, a medication to help prevent bone breakdown will improve or prevent bone loss in this condition.

Primary Outcome

Percent change in postero-anterior (PA) spine bone mineral density as measured by dual energy x-ray absorptiometry (DXA)over a 12-month period. The differences in log-transformed values are reported as percent change.

Interventions

  • DRUG Testosterone
  • DRUG Actonel (risedronate)
  • DRUG Placebo Actonel (risedronate)
  • DRUG Placebo testosterone

Trial Details

FieldValue
Enrollment Target 77 participants
Start Date 2003-06
Est. Completion 2008-04
Phase Phase 2
Massachusetts General Hospital

2,032 total trials

What the finished NCT00089843 record still lists

NCT00089843 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 77 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (42% lower).

The record links to 0 conditions, and to 4 interventions - of which Testosterone is the first listed.

NCT00089843 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00089843 about?

NCT00089843 is a clinical study titled "Bone Loss in Women With Anorexia Nervosa". Women with Anorexia Nervosa have been found to have low bone density. The study will determine whether administration of low doses of a natural hormone, testosterone and/or risedronate, a medication to help prevent bone breakdown will improve or prevent bone loss in this condition.

What is the current status of trial NCT00089843?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 77 participants. The study started on 2003-06. Estimated completion is 2008-04.

What interventions are being tested in trial NCT00089843?

The interventions under investigation include: Testosterone (DRUG), Actonel (risedronate) (DRUG), Placebo Actonel (risedronate) (DRUG), Placebo testosterone (DRUG).

Who is sponsoring clinical trial NCT00089843?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00089843's enrollment target sits among peer trials

77 891st of 2000 higher than 1,108 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00089843, the US trial registry maintained by the National Library of Medicine. NCT00089843 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.