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NCT03118479 · ClinicalTrials.gov registry record · Phase 1
Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH)
A Phase 1 study, sponsored by Massachusetts General Hospital.
- Terminated
- Registry status
- Phase 1
- Development phase
- 7
- Enrollment target
NCT03118479: Clinical Trial Phase 1 study, sponsored by Massachusetts General Hospital.
NCT03118479 is a Phase 1 study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 7 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03118479, a Phase 1 study, was terminated before completion, sponsored by Massachusetts General Hospital.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
The investigators are doing this research study to look at the relationship between testosterone (the main sex hormone in men) and insulin (the hormone that controls blood sugar levels) in men with Idiopathic Hypogonadotropic Hypogonadism (IHH). The investigators hypothesize that normalizing testosterone levels in men with IHH enhances insulin sensitivity, reduces visceral fat, increases lean body mass, and improves the lipid profile.
Primary Outcome
Response to 75 g glucose load
Interventions
- DRUG Testosterone
- DRUG Placebo Oral Tablet
- DRUG Anastrozole Pill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2010-05 |
| Est. Completion | 2010-09-01 |
| Phase | Phase 1 |
Why NCT03118479 stopped before completion
NCT03118479 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 3 interventions - of which Testosterone is the first listed.
NCT03118479 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03118479 about?
NCT03118479 is a clinical study titled "Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH)". The investigators are doing this research study to look at the relationship between testosterone (the main sex hormone in men) and insulin (the hormone that controls blood sugar levels) in men with Idiopathic Hypogonadotropic Hypogonadism (IHH). The investigators hypothesize that normalizing testos...
What is the current status of trial NCT03118479?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2010-05. Estimated completion is 2010-09-01.
What interventions are being tested in trial NCT03118479?
The interventions under investigation include: Testosterone (DRUG), Placebo Oral Tablet (DRUG), Anastrozole Pill (DRUG).
Who is sponsoring clinical trial NCT03118479?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03118479's enrollment target sits among peer trials
7 1972nd of 2000 higher than 27 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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