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NCT01098045 · ClinicalTrials.gov registry record
HIV Fat Redistribution and the Evaluation of Brown Fat
A clinical trial, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 27
- Enrollment target
NCT01098045: Completed study, sponsored by Massachusetts General Hospital.
NCT01098045 is a clinical trial that has completed, run by Massachusetts General Hospital. The registered enrollment target is 27 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01098045 has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 27 participants
- Enrollment target
Study Summary
The specific aims of this study are to determine whether HIV-infected patients with significant fat redistribution and ectopic fat accumulation have increased brown adipose tissue using 18F-FDG Positron Emission Tomography techniques. Recent studies suggest down regulation of Dicer, a major component of miRNA has an important role in the differentiation and function of brown and white adipose tissue and may contribute to lipodystrophy. Therefore we will expand on recent research in this area by recruiting HIV-infected men with lipodystrophy. We will perform subcutaneous fat biopsies of the dorsocervical and abdominal fat in a subset of HIV-infected and non-HIV-infected men in order to explore further the question of down regulation of Dicer and its implication on metabolic abnormalities in this population.
Primary Outcome
Brown Fat will be assessed by PET FDG
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2010-03 |
| Est. Completion | 2015-08 |
What the finished NCT01098045 record still lists
NCT01098045 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 27 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01098045 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01098045 about?
NCT01098045 is a clinical study titled "HIV Fat Redistribution and the Evaluation of Brown Fat". The specific aims of this study are to determine whether HIV-infected patients with significant fat redistribution and ectopic fat accumulation have increased brown adipose tissue using 18F-FDG Positron Emission Tomography techniques. Recent studies suggest down regulation of Dicer, a major compone...
What is the current status of trial NCT01098045?
This trial is currently completed. The enrollment target is 27 participants. The study started on 2010-03. Estimated completion is 2015-08.
Who is sponsoring clinical trial NCT01098045?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
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