Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,742 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
1,284 of 1,487 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (86.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
2,032 total, page 29 of 41
Somatosensory Profiling in Radicular Pain Patients And it's Correlation With Treatment Outcome
NCT02130258
CRLX101 in Combination With Bevacizumab for Recurrent Ovarian/Tubal/Peritoneal Cancer
NCT01652079
Cystic Fibrosis Related Bone Disease: the Role of CFTR
NCT01549314
Midodrine for the Treatment of Refractory Hypotension
NCT01531959
A Brain Imaging Study of Opioid (Morphine) and Non-opioid (Ketorolac) Conditioning Effects
NCT01576276
Ketamine Infusion for Treatment-resistant Major Depressive Disorder
NCT01582945
Potential Use Of Brain Network Activation Analysis to Diagnose Major Depression
NCT01579942
Two Stepped Care Models for Posttraumatic Stress Disorder (PTSD) Among Cambodian Refugees With PTSD
NCT01542372
Outcome of Patients With Mild Head Injury and Presence of an Acute Traumatic Abnormality on CT Scan of Head
NCT04143347
Consequences of Obstructive Sleep Apnea on Respiratory Function Following Weight-loss Surgery
NCT01697878
Brentuximab Vedotin Plus AVD in Limited-stage Hodgkin Lymphoma
NCT01534078
Incidence of Sleep-disordered Breathing and Upper Airway Collapsibility in Postpartum Patients and Its Intervention
NCT01719224
Validation of Electrical Cardiometry Versus Fick Method in Cardiac Output Measurement
NCT01568619
Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting
NCT01529502
Biomonitoring and Cardiorenal Syndrome in Heart Failure(BIONICS-HF) Trial
NCT01570153
Proton Radiation Therapy With Cisplatin and Etoposide Followed by Surgery in Stage III Non-Small Cell Lung Cancer
NCT01565772
Inositol and Omega-3 Fatty Acids in Pediatric Mania
NCT01396486
Comparison of Temporal to Pulmonary Artery Temperature Measurement in Patients With Fever
NCT01503294
Study to Image the Esophagus Using the OFDI Capsule
NCT02204150
A Study Assessing the Impact of Dermatology Consultation in Patients Presenting With Possible Cellulitis
NCT01795092
Endoscopic Myotomy for the Treatment of Achalasia (Motility Disorder) of the Esophagus - POEM Procedure
NCT01873300
Omega-3 Fatty Acid Supplementation to ADHD Pharmacotherapy in ADHD Adults With Deficient Emotional Self-Regulation Traits
NCT01399827
Tai Chi Intervention for Chinese Americans With Depression
NCT01619631
Stimulant Enhancement of Well-Being Therapy for Depression
NCT01478113
Monitoring and Modifying Atherosclerosis in Psoriasis Patients Study
NCT01522742
Endoscopic Therapy of Malignant Bile Duct Strictures
NCT01543607
Effect of Intranasal Oxytocin on Appetite and Caloric Intake in Men and Women
NCT01513499
Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIV
NCT01407237
Eplerenone in HIV Associated Abdominal Fat Accumulation
NCT01405456
A Prospective Study of a New Non-Invasive Cardiac Output Monitor in Children Undergoing General Anesthesia
NCT01499615
Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids
NCT01388764
Evaluation of a Combined Near Infrared Spectroscopy (NIRS) and Intravascular Ultrasound (IVUS) Catheter for Detection of Lipid Rich Plaque
NCT01506960
Reduced Intensity Double Umbilical Cord Blood Transplantation
NCT01408563
Mass in Motion Kids in the Clinical Setting
NCT02110615
Burn Outcomes in Young Adult Burn Survivors
NCT01254357
Evaluation of BIS for Quantification of Lymphedema
NCT01544335
LDE225 With Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan for Untreated Advanced Pancreatic Cancer
NCT01485744
The Influence of Pressure Pain on [11C]Diprenorphine Binding Potentials
NCT01546155
Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance
NCT02115646
Neural Correlates of Stress Reduction
NCT01488422
Efficacy, Safety and Tolerability of Icatibant for the Treatment of HAE
NCT01457430
11C Acetate Imaging Post Prostatectomy
NCT01602783
Pharmacogenomics for Antidepressant Guidance and Education
NCT01555021
Psychophysiological Indicators of Performance in Computer-Based Simulation
NCT01509794
A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
NCT01495390
Complex Dynamic Systems in Mood Disorders
NCT01583569
Bortezomib Plus Rituximab for EBV+ PTLD
NCT01058239
Effects of Pennsaid on Clinical Neuropathic Pain
NCT01508676
Effect of Nuvigil on Fatigue
NCT01460628
Cabozantinib in Women With Metastatic Hormone-Receptor-Positive Breast Cancer
NCT01441947
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Massachusetts General Hospital: open-pipeline peers nationwide
Peers matched on 2,032 registered trials and 17% open enrollment, not the therapeutic-area sidebar.
Massachusetts General Hospital sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 2,032 trials (± recruiting share)
- National Institute of Allergy and Infectious Diseases (NIAID) · 2,006 trials · 8% recruiting
- Memorial Sloan Kettering Cancer Center · 1,884 trials · 17% recruiting
- Pfizer · 1,845 trials · 6% recruiting
- Stanford University · 1,744 trials · 15% recruiting
Sponsors near 17% open enrollment (± trial volume)
- Rush University Medical Center · 17% recruiting · 320 trials
- OHSU Knight Cancer Institute · 17% recruiting · 211 trials
- Adagene · 17% recruiting · 6 trials
- Agendia · 17% recruiting · 6 trials
Related
What to do with this Massachusetts General Hospital page
2,032 registered trials is a research-attention snapshot, not an endorsement of Massachusetts General Hospital or any single study.
- 336 of Massachusetts General Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Depression is the condition Massachusetts General Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Depression trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Massachusetts General Hospital pipeline card: 2,032 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.