Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 29 of 41

COMPLETED NA

Somatosensory Profiling in Radicular Pain Patients And it's Correlation With Treatment Outcome

NCT02130258

COMPLETED Phase 2

CRLX101 in Combination With Bevacizumab for Recurrent Ovarian/Tubal/Peritoneal Cancer

NCT01652079

COMPLETED

Cystic Fibrosis Related Bone Disease: the Role of CFTR

NCT01549314

COMPLETED Phase 3

Midodrine for the Treatment of Refractory Hypotension

NCT01531959

COMPLETED NA

A Brain Imaging Study of Opioid (Morphine) and Non-opioid (Ketorolac) Conditioning Effects

NCT01576276

COMPLETED NA

Ketamine Infusion for Treatment-resistant Major Depressive Disorder

NCT01582945

TERMINATED

Potential Use Of Brain Network Activation Analysis to Diagnose Major Depression

NCT01579942

TERMINATED Phase 4

Two Stepped Care Models for Posttraumatic Stress Disorder (PTSD) Among Cambodian Refugees With PTSD

NCT01542372

COMPLETED

Outcome of Patients With Mild Head Injury and Presence of an Acute Traumatic Abnormality on CT Scan of Head

NCT04143347

COMPLETED NA

Consequences of Obstructive Sleep Apnea on Respiratory Function Following Weight-loss Surgery

NCT01697878

COMPLETED Phase 2

Brentuximab Vedotin Plus AVD in Limited-stage Hodgkin Lymphoma

NCT01534078

COMPLETED NA

Incidence of Sleep-disordered Breathing and Upper Airway Collapsibility in Postpartum Patients and Its Intervention

NCT01719224

COMPLETED

Validation of Electrical Cardiometry Versus Fick Method in Cardiac Output Measurement

NCT01568619

COMPLETED Phase 2

Pilot Study About the Harmful Effects of Blood Storage on Overweight People and the Role of iNO in This Setting

NCT01529502

COMPLETED

Biomonitoring and Cardiorenal Syndrome in Heart Failure(BIONICS-HF) Trial

NCT01570153

TERMINATED Phase 1

Proton Radiation Therapy With Cisplatin and Etoposide Followed by Surgery in Stage III Non-Small Cell Lung Cancer

NCT01565772

COMPLETED Phase 4

Inositol and Omega-3 Fatty Acids in Pediatric Mania

NCT01396486

COMPLETED

Comparison of Temporal to Pulmonary Artery Temperature Measurement in Patients With Fever

NCT01503294

COMPLETED NA

Study to Image the Esophagus Using the OFDI Capsule

NCT02204150

COMPLETED NA

A Study Assessing the Impact of Dermatology Consultation in Patients Presenting With Possible Cellulitis

NCT01795092

COMPLETED Phase 1

Endoscopic Myotomy for the Treatment of Achalasia (Motility Disorder) of the Esophagus - POEM Procedure

NCT01873300

COMPLETED Phase 2

Omega-3 Fatty Acid Supplementation to ADHD Pharmacotherapy in ADHD Adults With Deficient Emotional Self-Regulation Traits

NCT01399827

COMPLETED NA

Tai Chi Intervention for Chinese Americans With Depression

NCT01619631

TERMINATED NA

Stimulant Enhancement of Well-Being Therapy for Depression

NCT01478113

TERMINATED

Monitoring and Modifying Atherosclerosis in Psoriasis Patients Study

NCT01522742

TERMINATED NA

Endoscopic Therapy of Malignant Bile Duct Strictures

NCT01543607

COMPLETED Early Phase 1

Effect of Intranasal Oxytocin on Appetite and Caloric Intake in Men and Women

NCT01513499

COMPLETED

Physiologic Investigation of the Renin Angiotensin Aldosterone Axis in HIV

NCT01407237

COMPLETED NA

Eplerenone in HIV Associated Abdominal Fat Accumulation

NCT01405456

COMPLETED

A Prospective Study of a New Non-Invasive Cardiac Output Monitor in Children Undergoing General Anesthesia

NCT01499615

COMPLETED Phase 1

Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids

NCT01388764

TERMINATED Phase 4

Evaluation of a Combined Near Infrared Spectroscopy (NIRS) and Intravascular Ultrasound (IVUS) Catheter for Detection of Lipid Rich Plaque

NCT01506960

COMPLETED Phase 2

Reduced Intensity Double Umbilical Cord Blood Transplantation

NCT01408563

COMPLETED NA

Mass in Motion Kids in the Clinical Setting

NCT02110615

COMPLETED

Burn Outcomes in Young Adult Burn Survivors

NCT01254357

COMPLETED

Evaluation of BIS for Quantification of Lymphedema

NCT01544335

COMPLETED Phase 1

LDE225 With Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan for Untreated Advanced Pancreatic Cancer

NCT01485744

COMPLETED NA

The Influence of Pressure Pain on [11C]Diprenorphine Binding Potentials

NCT01546155

COMPLETED NA

Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance

NCT02115646

COMPLETED NA

Neural Correlates of Stress Reduction

NCT01488422

COMPLETED Phase 4

Efficacy, Safety and Tolerability of Icatibant for the Treatment of HAE

NCT01457430

TERMINATED NA

11C Acetate Imaging Post Prostatectomy

NCT01602783

TERMINATED

Pharmacogenomics for Antidepressant Guidance and Education

NCT01555021

COMPLETED NA

Psychophysiological Indicators of Performance in Computer-Based Simulation

NCT01509794

COMPLETED

A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers

NCT01495390

COMPLETED

Complex Dynamic Systems in Mood Disorders

NCT01583569

COMPLETED Phase 2

Bortezomib Plus Rituximab for EBV+ PTLD

NCT01058239

COMPLETED NA

Effects of Pennsaid on Clinical Neuropathic Pain

NCT01508676

COMPLETED Phase 4

Effect of Nuvigil on Fatigue

NCT01460628

COMPLETED Phase 2

Cabozantinib in Women With Metastatic Hormone-Receptor-Positive Breast Cancer

NCT01441947

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Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.