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NCT01513499 · ClinicalTrials.gov registry record · Early Phase 1
Effect of Intranasal Oxytocin on Appetite and Caloric Intake in Men and Women
A Early Phase 1 study of Eating Behavior, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT01513499: Completed Early Phase 1 study of Eating Behavior, sponsored by Massachusetts General Hospital.
NCT01513499 is a Early Phase 1 study of Eating Behavior that has completed, run by Massachusetts General Hospital. The registered enrollment target is 25 participants, below the 175-participant average among 20 other Eating Behavior trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01513499, a Early Phase 1 study of Eating Behavior, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
Exciting advances have led to the concept that hormones can modulate appetite and food intake. Oxytocin is a peptide hormone that is released in regions throughout the brain, including areas involved in food motivation. Animal studies suggest that oxytocin may reduce food intake. The effects of oxytocin administration on eating behavior in humans, which could have important implications in eating-related disorders ranging from obesity to anorexia nervosa, have not been investigated. This double-blind placebo-controlled cross-over study of single-dose oxytocin administration investigates whether: 1. Caloric intake will decrease following administration of oxytocin versus placebo 2. Appetite will decrease following administration of oxytocin versus placebo 3. Resting energy expenditure will increase following administration of oxytocin versus placebo
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Oxytocin
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2012-01 |
| Est. Completion | 2014-01 |
| Phase | Early Phase 1 |
What the finished NCT01513499 record still lists
NCT01513499 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 175-participant average among 20 other Eating Behavior trials with a reported enrollment target (86% lower).
The record links to 1 condition, with Eating Behavior appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT01513499 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01513499 about?
NCT01513499 is a clinical study titled "Effect of Intranasal Oxytocin on Appetite and Caloric Intake in Men and Women". Exciting advances have led to the concept that hormones can modulate appetite and food intake. Oxytocin is a peptide hormone that is released in regions throughout the brain, including areas involved in food motivation. Animal studies suggest that oxytocin may reduce food intake. The effects of oxyt...
What is the current status of trial NCT01513499?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 25 participants. The study started on 2012-01. Estimated completion is 2014-01.
What conditions does trial NCT01513499 study?
This clinical trial studies the following conditions: Eating Behavior.
What interventions are being tested in trial NCT01513499?
The interventions under investigation include: Placebo (DRUG), Oxytocin (DRUG).
Who is sponsoring clinical trial NCT01513499?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01513499 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Eating Behavior
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01513499's enrollment target sits among peer trials
25 19th of 20 higher than 2 of 20 other Eating Behavior trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Eating Behavior trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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