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NCT01576276 · ClinicalTrials.gov registry record · NA
A Brain Imaging Study of Opioid (Morphine) and Non-opioid (Ketorolac) Conditioning Effects
A NA study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- NA
- Development phase
- 51
- Enrollment target
NCT01576276: Completed NA study, sponsored by Massachusetts General Hospital.
NCT01576276 is a NA study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 51 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01576276, a NA study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 51 participants
- Enrollment target
Study Summary
Healthy right-handed volunteers aged 21 to 50 needed for a research study of the effects of morphine and ketorolac on brain activity in response to pain stimuli as measured by functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET). Study will be conducted on six separate days not requiring an overnight stay in the hospital.
Primary Outcome
Obtain information about brain activity, including BOLD (Blood-oxygen-level dependent) signal, using an fMRI system. Data analysis was applied using SPM 12 with a standard pipeline.
Interventions
- DRUG Ketorolac
- RADIATION Integrated MR-PET scan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 51 participants |
| Start Date | 2012-04 |
| Est. Completion | 2017-02 |
| Phase | NA |
What the finished NCT01576276 record still lists
NCT01576276 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 51 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Ketorolac is the first listed.
NCT01576276 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01576276 about?
NCT01576276 is a clinical study titled "A Brain Imaging Study of Opioid (Morphine) and Non-opioid (Ketorolac) Conditioning Effects". Healthy right-handed volunteers aged 21 to 50 needed for a research study of the effects of morphine and ketorolac on brain activity in response to pain stimuli as measured by functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET). Study will be conducted on six separate...
What is the current status of trial NCT01576276?
This trial is currently completed. It is a NA study. The enrollment target is 51 participants. The study started on 2012-04. Estimated completion is 2017-02.
What interventions are being tested in trial NCT01576276?
The interventions under investigation include: Ketorolac (DRUG), Integrated MR-PET scan (RADIATION).
Who is sponsoring clinical trial NCT01576276?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01576276's enrollment target sits among peer trials
51 1279th of 2000 higher than 722 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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