Massachusetts General Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).

2,032 total trials 336 currently recruiting 1284 completed early-phase tilt top decile by trial count

Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.

Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.

Top-decile sponsor footprint

Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,032 total, page 30 of 41

COMPLETED NA

Integrated Treatment for Smoking Cessation & Anxiety in People With HIV

NCT01393301

COMPLETED NA

The Effect of Oxytocin on Fear Memory Consolidation Novel Intervention to Prevent Posttraumatic Stress Disorder (PTSD)

NCT01466127

COMPLETED NA

Safety Study of Continuous Positive Airway Pressure Via a Nasal Mask

NCT01524614

COMPLETED NA

Development and Testing of Adolescent Twelve-Step Facilitation

NCT01449981

COMPLETED NA

HIV Prevention and Trauma Treatment for Men Who Have Sex With Men With Childhood Sexual Abuse Histories

NCT01395979

COMPLETED NA

IGF-1 and Bone Loss in Women With Anorexia Nervosa

NCT01406444

TERMINATED Phase 2

Testosterone and Alendronate in Hypogonadal Men

NCT01460654

COMPLETED NA

Growth Hormone Treatment on Phosphocreatine Recovery in Obesity

NCT01421589

COMPLETED Phase 1

Safety of Lactobacillus Rhamnosus GG Vs. Placebo in Elderly Subjects Receiving Trivalent Inactivated Influenza Vaccine

NCT01368029

COMPLETED Phase 1

Elucidating Kisspeptin Physiology by Blocking Kisspeptin Signaling

NCT01438073

TERMINATED Phase 2

A New Micrografting Technique for Vitiligo

NCT01262547

TERMINATED NA

Secondary Intention Wound Healing Versus Micrografting in Patients Undergoing Mohs Surgery

NCT01442844

TERMINATED Early Phase 1

Proton Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer

NCT01525446

COMPLETED

Olfactory Deficits in Neurologic Disease

NCT05019014

COMPLETED Phase 1

Sorafenib Maintenance Therapy for Patients With AML After Allogeneic Stem Cell Transplant

NCT01398501

COMPLETED Phase 1

Nilotinib With Radiation for High Risk Chordoma

NCT01407198

COMPLETED NA

Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder

NCT01453439

COMPLETED Phase 1

Midostaurin (PKC412) for Locally Advanced Rectal Cancer

NCT01282502

COMPLETED NA

Non-Invasive Imaging for Cording in Breast Cancer Patients

NCT01427166

COMPLETED

Natural History of Hopelessness, Suicidality, and Optimism in Psychiatric Inpatients Following Discharge

NCT01599247

COMPLETED NA

Optimizing Tattoo Removal: a Side-by-side Comparison in the Search for One Treatment Tattoo Removal

NCT01624688

COMPLETED NA

2/2 D-Cycloserine Augmentation of CBT for Pediatric OCD

NCT01404208

COMPLETED NA

Population-Based Patient-Centric Care: Comprehensive Preventive Cancer Screening Using Health IT

NCT01372527

COMPLETED NA

Neuromonitoring During the Latarjet Procedure

NCT01621126

TERMINATED Phase 4

Study of Probiotic GanedenBC30 for Irritable Bowel Syndrome and Major Depressive Disorder

NCT01337609

TERMINATED Phase 2

Panobinostat With Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma

NCT01282476

COMPLETED NA

Development of a Positive Psychology Intervention to Reduce Suicide Risk

NCT01398891

COMPLETED Phase 3

Cognitive Remediation With D-Cycloserine

NCT01399866

COMPLETED NA

Comparative Effectiveness Research for Eliminating Disparities

NCT02027636

COMPLETED NA

Optimal Dose of Succinylcholine and Rocuronium for Electroconvulsive Therapy (ECT)

NCT01441960

COMPLETED NA

Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies

NCT01401907

TERMINATED Early Phase 1

Evaluating Tumor Pseudoprogression With FLT-PET and MRI

NCT01105988

COMPLETED

Brain Genomics Superstruct Project

NCT01552460

COMPLETED Phase 1

Cabozantinib (XL184) in Men With Castrate-Resistant Prostate Cancer

NCT01347788

COMPLETED Phase 2

Bosutinib in Adult Patients With Recurrent Glioblastoma

NCT01331291

COMPLETED

Attentional Bias in Body Dysmorphic Disorder

NCT01398904

COMPLETED NA

Laparoscopy-Assisted Transanal Endoscopy Rectosigmoid Resection for Rectal Cancer

NCT01340755

COMPLETED NA

Quantification of Outcome Measures for Mind-body Interventions

NCT01308970

COMPLETED NA

A Pilot Study to Test the Safety and Feasibility of a Brillouin Ocular Analyzer

NCT01775007

COMPLETED NA

Oral Peanut Immunotherapy

NCT01324401

TERMINATED

Brain Activity Flow Patterns Analysis Using Evoked Response Potentials in Youth With ADHD, Bipolar Disorder, or Autism Spectrum Disorders: A Preliminary Study

NCT01506232

COMPLETED Phase 2

Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation

NCT01288235

COMPLETED NA

Understanding Mechanisms of Acquired Resistance to BIBW2992

NCT01074177

COMPLETED Phase 3

Effects of Anorexia Nervosa on Peak Bone Mass

NCT01301183

COMPLETED

Effect of Growth Hormone (GH) on Cardiac Echos in GH Deficient Patients After Acromegaly Treatment

NCT01302652

COMPLETED

Defining 31Phosphorous Magnetic Resonance Spectroscopy Characteristics in Patients With Mitochondrial Myopathy

NCT01301235

COMPLETED

Predictors of the Ability to Protect the Airway in Long-term Ventilated Patients

NCT01618240

COMPLETED Phase 1

Transcutaneous Immunization With an Attenuated Listeria Monocytogenes Vector Vaccine

NCT01311817

TERMINATED NA

Clinical Study to Evaluate the Effect of pH on Pain Upon Local Anesthetic Administration.

NCT01304082

TERMINATED

Risks for Insulin Resistance and Metabolic Syndrome Between Major Depressive Disorder (MDD) or MDD With Psychotic Features

NCT01310140

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Phase Distribution

PhaseTrial count
Phase 1 226
Phase 2 289
Phase 3 58
Phase 4 182

What is open in the Massachusetts General Hospital pipeline

336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).

Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).

Top condition: Depression (29 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.