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NCT02312102 · ClinicalTrials.gov registry record · Phase 1

Velcade and Lenalidomide in Patients With Relapsed AML and MDS After Allogeneic Stem Cell Transplantation

A Phase 1 study, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 1
Development phase
22
Enrollment target

NCT02312102: Completed Phase 1 study, sponsored by Massachusetts General Hospital.

NCT02312102 is a Phase 1 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 22 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02312102, a Phase 1 study, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 1
Development phase
22 participants
Enrollment target

Study Summary

This research study is evaluating drugs called bortezomib and lenalidomide as a possible treatment for myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). The purpose of this research study is to determine the safety and efficacy of the bortezomib and lenalidomide investigational combination. This drug combination has been used in the treatment of relapsed/refractory multiple myeloma and has been previously investigated in the treatment of MDS and AML, albeit at a lower dose of lenalidomide. In this research study, the investigators are looking for the highest dose of the combination that can be given safely and see how well it works as a combination for MDS and AML in individuals whose disease has relapsed after an SCT.

Interventions

  • DRUG Lenalidomide
  • DRUG Velcade

Trial Details

FieldValue
Enrollment Target 22 participants
Start Date 2015-02
Est. Completion 2024-10-07
Phase Phase 1

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT02312102

The ClinicalTrials.gov registry entry for NCT02312102 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Lenalidomide is the first listed.

NCT02312102 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02312102 about?

NCT02312102 is a clinical study titled "Velcade and Lenalidomide in Patients With Relapsed AML and MDS After Allogeneic Stem Cell Transplantation". This research study is evaluating drugs called bortezomib and lenalidomide as a possible treatment for myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). The purpose of this research study is to determine the safety and efficacy of the bortezomib and lenalidomide investigational combin...

What is the current status of trial NCT02312102?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2015-02. Estimated completion is 2024-10-07.

What interventions are being tested in trial NCT02312102?

The interventions under investigation include: Lenalidomide (DRUG), Velcade (DRUG).

Who is sponsoring clinical trial NCT02312102?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.