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NCT02314364 · ClinicalTrials.gov registry record · Phase 2
A Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLC
A Phase 2 study, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 27
- Enrollment target
NCT02314364: Completed Phase 2 study, sponsored by Massachusetts General Hospital.
NCT02314364 is a Phase 2 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 27 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02314364, a Phase 2 study, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 27 participants
- Enrollment target
Study Summary
This research study is studying a type of radiation therapy called Stereotactic Body Radiation Therapy (SBRT) as a possible treatment for stage IV non-small cell lung cancer (NSCLC) that has a mutated epidermal growth factor receptor (EGFR) or or displaced anaplastic lymphoma receptor tyrosine kinase (ALK) or ROS proto-oncogene 1 (ROS1) gene (= oncogene-driven NSCLC) and for which the subject has been receiving treatment with a targeted biological agent such as erlotinib, crizotinib, or other drugs.
Primary Outcome
Distant failures (DF) are defined as metastases outside areas that originally contained disease. The 1-year frequency of DF is defined as the percentage of patients that experienced a DF, respectively, over the course of one year.
Interventions
- RADIATION SBRT with protons or photons
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2014-12 |
| Est. Completion | 2023-10-25 |
| Phase | Phase 2 |
What the finished NCT02314364 record still lists
NCT02314364 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 1 intervention - of which SBRT with protons or photons is the first listed.
NCT02314364 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02314364 about?
NCT02314364 is a clinical study titled "A Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLC". This research study is studying a type of radiation therapy called Stereotactic Body Radiation Therapy (SBRT) as a possible treatment for stage IV non-small cell lung cancer (NSCLC) that has a mutated epidermal growth factor receptor (EGFR) or or displaced anaplastic lymphoma receptor tyrosine kinas...
What is the current status of trial NCT02314364?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2014-12. Estimated completion is 2023-10-25.
What interventions are being tested in trial NCT02314364?
The interventions under investigation include: SBRT with protons or photons (RADIATION).
Who is sponsoring clinical trial NCT02314364?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02314364's enrollment target sits among peer trials
27 1697th of 2000 higher than 293 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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