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NCT04294888 · ClinicalTrials.gov registry record · NA

TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory

A NA study, sponsored by Massachusetts General Hospital.

Terminated
Registry status
NA
Development phase
4
Enrollment target

NCT04294888: Clinical Trial NA study, sponsored by Massachusetts General Hospital.

NCT04294888 is a NA study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 4 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04294888, a NA study, was terminated before completion, sponsored by Massachusetts General Hospital.

TERMINATED
Registry status
NA
Development phase
4 participants
Enrollment target

Study Summary

The purpose of this study is to assess the effects of non-invasive brain stimulation on memory in cognitively unimpaired older adults and in patients amnestic mild cognitive impairment (aMCI) due to Alzheimer's disease (AD). This study will use repetitive Transcranial Magnetic Stimulation (rTMS) to stimulate nodes of the Default Mode Network (DMN)- which is thought to support episodic memory and to be affected by Alzheimer's pathology. We will use functional connectivity MRI (fcMRI) to assess changes in functional network architecture following the stimulation. We will also assess putative cognitive improvements resulting from the stimulation by in-depth memory testing.

Interventions

  • DEVICE repetitive transcranial magnetic stimulation (rTMS)

Trial Details

FieldValue
Enrollment Target 4 participants
Start Date 2020-03-02
Est. Completion 2021-06-23
Phase NA

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT04294888

The ClinicalTrials.gov registry entry for NCT04294888 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which repetitive transcranial magnetic stimulation (rTMS) is the first listed.

NCT04294888 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04294888 about?

NCT04294888 is a clinical study titled "TMS in Preclinical and Prodromal AD: Modulation of Brain Networks and Memory". The purpose of this study is to assess the effects of non-invasive brain stimulation on memory in cognitively unimpaired older adults and in patients amnestic mild cognitive impairment (aMCI) due to Alzheimer's disease (AD). This study will use repetitive Transcranial Magnetic Stimulation (rTMS) to ...

What is the current status of trial NCT04294888?

This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2020-03-02. Estimated completion is 2021-06-23.

What interventions are being tested in trial NCT04294888?

The interventions under investigation include: repetitive transcranial magnetic stimulation (rTMS) (DEVICE).

Who is sponsoring clinical trial NCT04294888?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.