Massachusetts General Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Massachusetts General Hospital sits in the top decile of US sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count).
Massachusetts General Hospital: 2,032 sponsored US clinical trials, 336 recruiting.
Massachusetts General Hospital sponsors 2,032 registered US clinical trials on ClinicalTrials.gov, 336 of them currently recruiting, and 1,284 completed. 240 of these trials are in Phase 3-4 (later-stage) and 515 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 29 trials.
Top-decile sponsor footprint
Massachusetts General Hospital ranks in the top decile of sponsors by registered trial count (#4 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
2,032 total, page 12 of 41
Assessing E-Cigarettes for Tobacco Harm Reduction in the Context of Lung Cancer Screening
NCT06472869
PACE CF, a 3-session Mind-body Pain Management Program for Adults With Cystic Fibrosis
NCT06606457
Project QUIT+: Adapting and Testing a Smoking Cessation Intervention for Transgender and Gender Expansive Individuals
NCT06654414
Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 1
NCT06287801
Open Pilot Trial of a Mind-body Program for Cardiac Arrest Survivors and Their Caregivers
NCT06517394
Virtual Reality Guided Acupuncture Imagery Treatment for Chronic Low Back Pain
NCT06814470
Open Pilot Trial of a Mind-Body Sexual Well-Being Intervention for Female GI Cancer Survivors
NCT06331403
D-Cycloserine for Serine Palmitoyltransferase Inhibition
NCT07542548
Communication Intervention for Fecal Ostomy Surgery
NCT06320002
The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial
NCT06075797
TMS as a Treatment for Apathy in Alzheimer's Disease
NCT05389644
The COMA Family Program: A Skills-Based Resiliency Program for Caregivers of Patients With Severe Acute Brain Injuries
NCT05761925
The Brain Metabolism of Unpredictable Signals
NCT05756335
Supporting Our Caregivers In ADRD Learning (SOCIAL)
NCT06276023
Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas
NCT06132165
Vaginal lIve Biotherapeutic RANdomized Trial
NCT06135974
Radio-Frequency Microneedling Device
NCT06228144
Brain Health Program for Older Adults With Subjective Cognitive Decline
NCT05934136
Adaptive Bridging RT in R/R B-cell Lymphoma (Pre-CAR T)
NCT06004167
Mobile App Psychological Interventions for Family Dementia Caregivers
NCT05253443
Effects Multimodal Mind and Body Approach for MCI
NCT06814483
Esophageal Cancer Multimodal Prehabilitation Study
NCT06027515
Testing the Integrated mHealth App Intervention "SiS-H"
NCT05886621
Comparative Effectiveness of Individual Versus Group-Level Interventions to Increase PrEP Uptake and Reduce HIV/STI Incidence
NCT06022809
Caring for Caregivers and People Living With Dementia Under Home-Based Primary Care
NCT05849259
Real-time Intervention for Suicide Risk Reduction
NCT05848089
Guideline Directed Medical Therapy in Patients With Heart Failure
NCT06700213
Using Non-Weightbearing Stationary Elliptical Machines for Patients with Chronic Low Back Pain
NCT05724160
Losartan in Prevention of Radiation-Induced Heart Failure
NCT05607017
MASC: Reducing Stress for Caregivers
NCT05847153
INF108F in Infants With Food Protein Induced Proctocolitis
NCT05793112
Behavioral Coaching Intervention (Laguna Health) for Patients With Cancer
NCT06004141
PROWESS (PROstate Cancer Wearables Exercise and Structured Supports): A Pilot Supportive Care Intervention
NCT05755490
Guided Meditation to Decrease Perioperative Anxiety and Increase Patient Intraoperative Compliance in Vascular Surgery
NCT05837481
Promoting Safety Plan and Coping Strategy Use Among Adults With Suicidal Thoughts
NCT05791643
Conditionally Increased Output (CIO) Enhanced Ultrasound System
NCT05792423
A Novel Cooling Device for Pain Management During Fingerstick Blood Draw
NCT05329493
Early Postoperative Function After Open Versus Ultrasound-Guided Trigger Finger Release
NCT07364695
Building Resiliency Among Caregivers of Curvivors and Metavivors
NCT05702723
Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening
NCT05714644
The 4th Trimester Initiative: The Impact of Parental Support on Pregnant Trainee Wellbeing
NCT06014892
Improving Health for Older Adults With Pain Through Engagement (Open-pilot)
NCT05782231
Nurse-Led Quality of Life Study-Phase I
NCT05853614
The Thrive Study: Improving Multimodal Physical Function in Adults With Heterogenous Chronic Pain
NCT05700383
Rapid Diagnostic Assay for Gonorrhea and Chlamydia
NCT05564299
Effect of a Targeted Notification and Clinical Support Pathway on Individuals With Left Ventricular Hypertrophy
NCT05713916
Precision Clinical and Genetic Tools for Brain Health in Hemorrhagic Stroke
NCT05643001
Breast Cancer Survivor Educational Intervention
NCT05700396
STRIDE: Stress Reduction in Dementia Caregivers
NCT05732038
Pain Reduction and Ovarian Perfusion Following Uterine Fibroid Embolization
NCT06106633
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 226 |
| Phase 2 | 289 |
| Phase 3 | 58 |
| Phase 4 | 182 |
Therapeutic Areas
What is open in the Massachusetts General Hospital pipeline
336 recruiting of 2,032 indexed (17% open); 1,284 completed (63%).
Phase mix: 240 late (III/IV) vs 515 early (I/II) (early-phase heavy).
Top condition: Depression (29 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.