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NCT07542548 · ClinicalTrials.gov registry record · Phase 4

D-Cycloserine for Serine Palmitoyltransferase Inhibition

A Phase 4 study, sponsored by Massachusetts General Hospital.

Completed
Registry status
Phase 4
Development phase
1
Enrollment target

NCT07542548: Completed Phase 4 study, sponsored by Massachusetts General Hospital.

NCT07542548 is a Phase 4 study that has completed, run by Massachusetts General Hospital. The registered enrollment target is 1 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT07542548, a Phase 4 study, has completed, sponsored by Massachusetts General Hospital.

COMPLETED
Registry status
Phase 4
Development phase
1 participants
Enrollment target

Study Summary

The overarching objective of this study is to mitigate the neurological decline associated with SPTSSA related Complex Hereditary Spastic Paraplegia

Primary Outcome

Frequency of treatment related serious adverse events as assessed by CTCAE Version 5.0

Interventions

  • DRUG D-cycloserine

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2024-07-10
Est. Completion 2026-03-17
Phase Phase 4
Massachusetts General Hospital

2,032 total trials

What the finished NCT07542548 record still lists

NCT07542548 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 1 intervention - of which D-cycloserine is the first listed.

NCT07542548 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07542548 about?

NCT07542548 is a clinical study titled "D-Cycloserine for Serine Palmitoyltransferase Inhibition". The overarching objective of this study is to mitigate the neurological decline associated with SPTSSA related Complex Hereditary Spastic Paraplegia

What is the current status of trial NCT07542548?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 1 participants. The study started on 2024-07-10. Estimated completion is 2026-03-17.

What interventions are being tested in trial NCT07542548?

The interventions under investigation include: D-cycloserine (DRUG).

Who is sponsoring clinical trial NCT07542548?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07542548's enrollment target sits among peer trials

1 2000th of 2000 the lowest of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07542548, the US trial registry maintained by the National Library of Medicine. NCT07542548 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.