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NCT05389644 · ClinicalTrials.gov registry record · NA
TMS as a Treatment for Apathy in Alzheimer's Disease
A NA study, sponsored by Massachusetts General Hospital.
- Terminated
- Registry status
- NA
- Development phase
- 3
- Enrollment target
NCT05389644: Clinical Trial NA study, sponsored by Massachusetts General Hospital.
NCT05389644 is a NA study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 3 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05389644, a NA study, was terminated before completion, sponsored by Massachusetts General Hospital.
- TERMINATED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
Study Summary
This proposal will demonstrate that non-invasive brain stimulation is able to modulate cortico-striatal circuits in neurodegenerative patients with apathy, and that doing so results in circuit-specific increases in FC and DA availability. These circuit changes will be accompanied by changes in specific behavioral dimensions of apathy. This work will lead to larger studies which develop personalized, circuit-specific neuromodulation strategies for AD patients suffering from this intractable neuropsychiatric symptom.
Interventions
- DEVICE Intermittent Theta Burst Stimulation (iTBS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2024-05-02 |
| Est. Completion | 2024-10-28 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05389644
The ClinicalTrials.gov registry entry for NCT05389644 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Intermittent Theta Burst Stimulation (iTBS) is the first listed.
NCT05389644 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05389644 about?
NCT05389644 is a clinical study titled "TMS as a Treatment for Apathy in Alzheimer's Disease". This proposal will demonstrate that non-invasive brain stimulation is able to modulate cortico-striatal circuits in neurodegenerative patients with apathy, and that doing so results in circuit-specific increases in FC and DA availability. These circuit changes will be accompanied by changes in speci...
What is the current status of trial NCT05389644?
This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2024-05-02. Estimated completion is 2024-10-28.
What interventions are being tested in trial NCT05389644?
The interventions under investigation include: Intermittent Theta Burst Stimulation (iTBS) (DEVICE).
Who is sponsoring clinical trial NCT05389644?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
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