Kyowa Kirin

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Kyowa Kirin sits in the top decile of US sponsors by registered trial count (#484 of 15,742 sponsors by registered trial count).

34 total trials 1 currently recruiting 27 completed early-phase tilt top decile by trial count

Kyowa Kirin: 34 sponsored US clinical trials, 1 recruiting.

Kyowa Kirin sponsors 34 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 27 completed. 8 of these trials are in Phase 3-4 (later-stage) and 25 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Parkinson's Disease, with 2 trials.

Top-decile sponsor footprint

Kyowa Kirin ranks in the top decile of sponsors by registered trial count (#484 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 57/100

27 of 31 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (87.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

34 total, page 1 of 1

RECRUITING

Post-authorization Safety Study of Allogeneic Hematopoietic Stem Cell Transplantation in Patients Treated With Mogamulizumab

NCT04014374

ACTIVE NOT RECRUITING Phase 2

Mogamulizumab Q4week Dosing in Participants With R/R CTCL

NCT04745234

NOT YET RECRUITING Phase 1

A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma

NCT07192471

COMPLETED Phase 1

Study to Assess Bioequivalence and Adhesion Properties Between Two Granisetron Transdermal Patches.

NCT05027646

COMPLETED Phase 1

Single-dose Study to Investigate the Plasma PK of KW-6356 and Its Major Metabolite

NCT04190654

TERMINATED Phase 1

KHK2455 (IDO Inhibitor) Plus Avelumab in Adult Subjects With Advanced Bladder Cancer

NCT03915405

COMPLETED Phase 1

Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-KW-6356

NCT04147910

COMPLETED Phase 2

Study of an Anti-OX40 Monoclonal Antibody (KHK4083) in Subjects With Moderate to Severe Atopic Dermatitis

NCT03703102

COMPLETED Phase 3

Efficacy and Safety of Burosumab Versus Oral Phosphate and Active Vitamin D Treatment in Pediatric Patients With XLH

NCT02915705

COMPLETED Phase 1

KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT02867007

COMPLETED Phase 2

Study of a Monoclonal Antibody KHK4083 in Moderate Ulcerative Colitis

NCT02647866

COMPLETED Phase 2

Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)

NCT02750618

COMPLETED Phase 1

Study of Mogamulizumab + Nivolumab in Subjects w/Locally Advanced or Metastatic Solid Tumors

NCT02705105

COMPLETED Phase 3

Open Label Study of KRN23 on Osteomalacia in Adults With X-linked Hypophosphatemia (XLH)

NCT02537431

COMPLETED Phase 3

Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)

NCT02526160

COMPLETED Phase 2

Study of Burosumab (KRN23) in Adults With Tumor-Induced Osteomalacia (TIO) or Epidermal Nevus Syndrome (ENS)

NCT02304367

COMPLETED Phase 2

Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)

NCT02312687

COMPLETED Phase 1

Study of Mogamulizumab + Docetaxel in Subjects With Non-small Cell Lung Cancer

NCT02358473

COMPLETED Phase 1

Study of Mogamulizumab + MEDI4736 (Durvalumab) and Mogamulizumab + Tremelimumab in Subjects w/ Advanced Solid Tumors

NCT02301130

COMPLETED Phase 2

Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)

NCT02163577

COMPLETED Phase 3

Study of KW-0761 Versus Vorinostat in Relapsed/Refractory CTCL

NCT01728805

COMPLETED Phase 2

KW-0761 or Investigator's Choice in Subjects With Previously Treated Adult T-cell Leukemia-Lymphoma (ATL)

NCT01626664

COMPLETED Phase 1

Phase I Study of KRN330 Monoclonal Antibody in Patients With Colorectal Cancer

NCT00575562

TERMINATED Phase 1

An Ascending Dose Study of KW-2449 in Acute Leukemias, Myelodysplastic Syndromes, and Chronic Myelogenous Leukemia

NCT00346632

TERMINATED Phase 3

An Extension of Istradefylline in North American Parkinson's Disease Patients Who Have Completed Study 6002-INT-001

NCT00199381

COMPLETED Phase 2

Study of Istradefylline (KW-6002) for the Treatment of Restless Legs Syndrome

NCT00199446

COMPLETED Phase 2

A Study of Istradefylline (KW-6002) as Monotherapy in Parkinson's Disease (PD) Patients

NCT00199433

TERMINATED Phase 1

A Study of a Monoclonal Antibody, KW-2871, in Patients With Advanced Melanoma

NCT00199342

COMPLETED Phase 3

An Extension of Istradefylline in Parkinson's Disease Patients Who Have Completed Studies 6002-EU-007, 6002-US-013 or 6002-US-018

NCT00199368

COMPLETED Phase 3

A Study of Istradefylline (KW-6002) in Treating Patients With Parkinson's Disease on Levodopa

NCT00199420

COMPLETED Phase 3

A Study of Istradefylline (KW-6002) for the Treatment of Parkinson's Disease in Patients Taking Levodopa

NCT00199407

COMPLETED Phase 2

A Long-Term, Safety Study With a Flexible Dose Range of KW-6002 in Patients With Motor Response Complications on Levodopa/Carbidopa Therapy

NCT00955045

COMPLETED Phase 2

12-Week, Double-Blind, Placebo-Controlled, Randomized Study of the Efficacy of 40 mg/Day KW-6002 in Parkinson's Disease Patients on Levodopa/Carbidopa

NCT00456586

COMPLETED Phase 2

12-Week, Double-Blind, Placebo-Controlled Study of 20 and 60 mg/Day Istradefylline in Parkinson's Disease Patients on Levodopa/Carbodopa

NCT00456794

What is open in the Kyowa Kirin pipeline

1 recruiting of 34 indexed (3% open); 27 completed (79%).

Phase mix: 8 late (III/IV) vs 25 early (I/II) (early-phase heavy).

Top condition: Parkinson's Disease (2 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Kyowa Kirin: open-pipeline peers nationwide

Peers matched on 34 registered trials and 3% open enrollment, not the therapeutic-area sidebar.

Kyowa Kirin sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150200250 0%10%20%30%40%50% Total trials Recruiting share Kyowa KirinAllegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)American RegentAmicus TherapeuticsCochlearIdorsia PharmaceuticalsKlein BuendelNational Center for Complementary and Integrative Health (NCCIH)Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Kyowa Kirin sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Kyowa Kirin sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 34 trials (± recruiting share)

Sponsors near 3% open enrollment (± trial volume)

What to do with this Kyowa Kirin page

34 registered trials is a research-attention snapshot, not an endorsement of Kyowa Kirin or any single study.

  • 1 of Kyowa Kirin's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Parkinson's Disease is the condition Kyowa Kirin studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Parkinson's Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Kyowa Kirin pipeline card: 34 registered trials from official public datasets.Report a data error.