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NCT02867007 · ClinicalTrials.gov registry record · Phase 1
KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors
A Phase 1 study, sponsored by Kyowa Kirin.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT02867007: Completed Phase 1 study, sponsored by Kyowa Kirin.
NCT02867007 is a Phase 1 study that has completed, run by Kyowa Kirin. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02867007, a Phase 1 study, has completed, sponsored by Kyowa Kirin.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
The purpose of this study is to characterize the safety, tolerability, and determine the maximum tolerated dose (MTD) or the highest protocol-defined dose, in the absence of exceeding the MTD, of KHK2455 administered orally in combination with mogamulizumab to subjects with locally advanced or metastatic solid tumors.
Primary Outcome
Safety assessment variables will include all adverse events (AEs) including serious and non-serious AEs, changes in clinical laboratory parameters, vital signs, 12-lead electrocardiograms, physical examination, and immunogenicity
Interventions
- DRUG Mogamulizumab
- DRUG KHK2455
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2016-08 |
| Est. Completion | 2019-12-15 |
| Phase | Phase 1 |
What the finished NCT02867007 record still lists
NCT02867007 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 2 interventions - of which Mogamulizumab is the first listed.
NCT02867007 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02867007 about?
NCT02867007 is a clinical study titled "KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors". The purpose of this study is to characterize the safety, tolerability, and determine the maximum tolerated dose (MTD) or the highest protocol-defined dose, in the absence of exceeding the MTD, of KHK2455 administered orally in combination with mogamulizumab to subjects with locally advanced or metas...
What is the current status of trial NCT02867007?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2016-08. Estimated completion is 2019-12-15.
What interventions are being tested in trial NCT02867007?
The interventions under investigation include: Mogamulizumab (DRUG), KHK2455 (DRUG).
Who is sponsoring clinical trial NCT02867007?
This trial is sponsored by Kyowa Kirin, which has 34 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02867007's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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