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NCT07192471 · ClinicalTrials.gov registry record · Phase 1

A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma

A Phase 1 study, sponsored by Kyowa Kirin.

Not yet
Registry status
Phase 1
Development phase
72
Enrollment target

NCT07192471: Clinical Trial Phase 1 study, sponsored by Kyowa Kirin.

NCT07192471 is a Phase 1 study that has not yet begun recruiting, run by Kyowa Kirin. The registered enrollment target is 72 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07192471, a Phase 1 study, has not yet begun recruiting, sponsored by Kyowa Kirin.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
72 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety, tolerability, PK and pharmacodynamics of KK2223 in adult participants with relapsed or refractory peripheral T cell lymphoma (PTCL) or cutaneous T cell lymphoma (CTCL).

Primary Outcome

Number of participants with treatment-related adverse events as assessed by CTCAE v5.0 (all 72 potentially treated subjects)

Interventions

  • DRUG KK2223

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2026-08
Est. Completion 2030-09
Phase Phase 1
Kyowa Kirin

34 total trials

What is known before NCT07192471 opens enrollment

NCT07192471 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher).

The record links to 0 conditions, and to 1 intervention - of which KK2223 is the first listed.

NCT07192471 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07192471 about?

NCT07192471 is a clinical study titled "A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma". The purpose of this study is to determine the safety, tolerability, PK and pharmacodynamics of KK2223 in adult participants with relapsed or refractory peripheral T cell lymphoma (PTCL) or cutaneous T cell lymphoma (CTCL).

What is the current status of trial NCT07192471?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2026-08. Estimated completion is 2030-09.

What interventions are being tested in trial NCT07192471?

The interventions under investigation include: KK2223 (DRUG).

Who is sponsoring clinical trial NCT07192471?

This trial is sponsored by Kyowa Kirin, which has 34 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07192471's enrollment target sits among peer trials

72 736th of 2000 higher than 1,254 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07192471, the US trial registry maintained by the National Library of Medicine. NCT07192471 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.