Idorsia Pharmaceuticals

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Idorsia Pharmaceuticals sits in the top decile of US sponsors by registered trial count (#484 of 15,742 sponsors by registered trial count).

34 total trials 1 currently recruiting 27 completed top decile by trial count

Idorsia Pharmaceuticals: 34 sponsored US clinical trials, 1 recruiting.

Idorsia Pharmaceuticals sponsors 34 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 27 completed. 14 of these trials are in Phase 3-4 (later-stage) and 17 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Insomnia Disorder, with 3 trials.

Top-decile sponsor footprint

Idorsia Pharmaceuticals ranks in the top decile of sponsors by registered trial count (#484 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 57/100

27 of 31 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (87.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

34 total, page 1 of 1

RECRUITING

Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ®

NCT06498128

ACTIVE NOT RECRUITING

Database Study to Provide Information on Pregnancy and Infant Outcomes Among Women Exposed to QUVIVIQ (Daridorexant)

NCT06393504

ACTIVE NOT RECRUITING Phase 3

A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease

NCT03737214

COMPLETED Phase 1

A Phase 1 Trial to Investigate the Biological Equivalence of 5 × 10 mg Tablets and 2 × 25 mg Tablets of Daridorexant in Healthy Male and Female Japanese Participants

NCT05877222

COMPLETED Phase 4

A Study to Find Out if Daridorexant is Safe and Efficacious in Patients With Insomnia and Comorbid Nocturia

NCT05597020

COMPLETED Phase 1

A Study to Measure Daridorexant in Breast Milk of Healthy Lactating Women

NCT05632393

COMPLETED Phase 2

Dose-finding Study Assessing the Efficacy, Safety, and Pharmacokinetics of Daridorexant in Subjects Aged 10 to < 18 Years With Insomnia Disorder

NCT05423717

COMPLETED Phase 2

Multicenter Study to Evaluate the Efficacy and Safety of Oral ACT-539313 in the Treatment of Adults With Moderate to Severe Binge Eating Disorder

NCT04753164

COMPLETED

Natural History Study for Pediatric Patients With Early Onset of Either GM1 Gangliosidosis, GM2 Gangliosidoses, or Gaucher Disease Type 2

NCT04470713

COMPLETED Phase 1

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects

NCT03869320

COMPLETED Phase 3

Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain, Caused by Bleeding Onto the Surface of the Brain

NCT03585270

COMPLETED Phase 3

Study to Assess the Long Term Safety and Tolerability of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep

NCT03679884

COMPLETED Phase 1

Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug Users

NCT03657355

COMPLETED Phase 1

A Study to Evaluate How Aprocitentan is Safe and How it is Absorbed and Broken Down in the Body of Japanese and Caucasian Subjects

NCT03586570

COMPLETED Phase 3

Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease

NCT03425539

COMPLETED Phase 3

A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety

NCT03541174

COMPLETED Phase 3

Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia Disorder

NCT03545191

COMPLETED Phase 3

Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep

NCT03575104

COMPLETED Phase 2

Study to Validate the Questionnaire Called IDSIQ™ in Patients With Insomnia Disorder

NCT03056053

COMPLETED Phase 2

Efficacy and Safety of ACT-541468 in Elderly Subjects With Insomnia Disorder

NCT02841709

COMPLETED Phase 2

Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia Disorder

NCT02839200

COMPLETED Phase 1

A Study to Investigate the Effect of ACT-132577 on the Pharmacokinetics of Midazolam and 1-hydroxy Midazolam in Healthy Male Subjects

NCT02841761

COMPLETED Phase 2

Dose-finding Study With ACT-132577 (Aprocitentan) in Participants With Essential Hypertension

NCT02603809

COMPLETED Phase 3

Efficacy, Safety, and Tolerability Study of ACT-129968 in Patients With Seasonal Allergic Rhinitis

NCT01484119

COMPLETED Phase 2

Clinical Study to Explore the Efficacy of ACT-129968 in Patients With Partly Controlled Asthma

NCT01225315

COMPLETED Phase 2

Study of ACT-129968 in Adult Patients With Seasonal Allergic Rhinitis

NCT01241214

TERMINATED Phase 2

Tezosentan in Patients With Pulmonary Arterial Hypertension

NCT01094067

TERMINATED Phase 2

Tezosentan in Pulmonary Arterial Hypertension

NCT01077297

TERMINATED Phase 3

Clazosentan in Aneurysmal Subarachnoid Hemorrhage

NCT00940095

COMPLETED Phase 3

Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Surgical Clipping

NCT00558311

TERMINATED Phase 3

Study of the Efficacy and Safety of Tezosentan in Patients With Pre-operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart Surgery

NCT00458276

COMPLETED Phase 2

Clazosentan in Preventing the Occurrence of Cerebral Vasospasm Following an Aneurysmal Subarachnoid Hemorrhage (aSAH)

NCT00111085

COMPLETED Phase 3

Tezosentan in Acute Heart Failure

NCT00525707

COMPLETED Phase 3

Tezosentan in the Treatment of Acute Heart Failure

NCT00524433

What is open in the Idorsia Pharmaceuticals pipeline

1 recruiting of 34 indexed (3% open); 27 completed (79%).

Phase mix: 14 late (III/IV) vs 17 early (I/II) (balanced across stages).

Top condition: Insomnia Disorder (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Idorsia Pharmaceuticals: open-pipeline peers nationwide

Peers matched on 34 registered trials and 3% open enrollment, not the therapeutic-area sidebar.

Idorsia Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150200250 0%10%20%30%40%50% Total trials Recruiting share Idorsia PharmaceuticalsAllegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)American RegentAmicus TherapeuticsCochlearKlein BuendelKyowa KirinNational Center for Complementary and Integrative Health (NCCIH)Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Idorsia Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Idorsia Pharmaceuticals sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 34 trials (± recruiting share)

Sponsors near 3% open enrollment (± trial volume)

What to do with this Idorsia Pharmaceuticals page

34 registered trials is a research-attention snapshot, not an endorsement of Idorsia Pharmaceuticals or any single study.

  • 1 of Idorsia Pharmaceuticals's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Insomnia Disorder is the condition Idorsia Pharmaceuticals studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Insomnia Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Idorsia Pharmaceuticals pipeline card: 34 registered trials from official public datasets.Report a data error.