EMD Serono

71 total trials 48 completed

EMD Serono sponsors 71 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 48 completed. 24 of these trials are in Phase 3-4 (later-stage) and 40 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Patients With Solid Tumors, Either Refractory to Standard Therapy or for Which no Effective Standard Therapy is Available, with 1 trials.

Trial Pipeline

71 total, page 1 of 2

TERMINATED Phase 2

Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Participant Who Participated in ADDRESS II)

NCT02070978

TERMINATED Phase 1

Sym004 in Subjects With Stage IV Non-small Cell Lung Cancer

NCT02083679

TERMINATED Phase 4

RESOunD: REbif Satisfaction On Discontinuing Oral Dimethyl Fumarate

NCT02117050

COMPLETED Phase 4

Rebif® Rebidose® Versus Rebiject II® Ease-of-Use

NCT02019550

TERMINATED Phase 3

Tecemotide Following Concurrent Chemo-radiotherapy for Non-small Cell Lung Cancer

NCT02049151

TERMINATED Phase 2

MSB0010445 and Stereotactic Body Radiation Therapy in Advanced Melanoma

NCT01973608

COMPLETED Phase 1

First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies

NCT01971515

COMPLETED Phase 2

Efficacy and Safety of Atacicept in Systemic Lupus Erythematosus

NCT01972568

COMPLETED Phase 1

Relative Bioavailability of Pimasertib in Cancer Patients

NCT01992874

TERMINATED Phase 2

Efficacy, Safety, and Tolerability of Plovamer Acetate (Pathway 1)

NCT01963611

COMPLETED Phase 2

Trial of Pimasertib With SAR245409 or Placebo in Ovarian Cancer

NCT01936363

TERMINATED

Adherence Trial With MS LifeLines ® Services

NCT01905527

COMPLETED Phase 2

Phase II Trial of Pimasertib Versus Dacarbazine in N-Ras Mutated Cutaneous Melanoma

NCT01693068

COMPLETED Phase 2

Tecemotide (L-BLP25) in Prostate Cancer

NCT01496131

TERMINATED Phase 1

MSC2015103B in Solid Tumors

NCT01453387

TERMINATED Phase 1

Atacicept in Lupus Nephritis Patients Taking Stable Regimen of Mycophenolate Mofetil

NCT01369628

TERMINATED Phase 1

Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus

NCT01378377

COMPLETED Phase 1

Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors

NCT01390818

COMPLETED Phase 2

EMD 525797 in Subjects With Asymptomatic or Mildly Symptomatic Metastatic Castrate-resistant Prostate Cancer

NCT01360840

TERMINATED Phase 3

Saizen® Solution for Injection Adult Growth Hormone Deficiency (GHD) Immunogenicity Study

NCT01237340

TERMINATED Phase 2

Phase 2 Extension Trial in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS)

NCT01226745

COMPLETED

Retrospective Cohort Study of Rebif® Use in Pediatric Multiple Sclerosis (MS) Subjects (REPLAY)

NCT01207648

COMPLETED Phase 4

Rebif Advanced Magnetic Resonance Imaging (MRI) and Immunology Pilot Trial

NCT01085318

TERMINATED Phase 1

First-in-Man, Dose-escalation Trial of c-Met Kinase Inhibitor EMD 1204831 in Subjects With Advanced Solid Tumors

NCT01110083

COMPLETED Phase 4

The REbif® vs Glatiramer Acetate in Relapsing Multiple Sclerosis Pharmacogenetics Trial

NCT01034579

COMPLETED Phase 3

A Multicenter, Open-label, RebiSmart™ Autoinjector Ease of Use Study

NCT01036165

COMPLETED Phase 2

EMD 1201081 in Combination With Cetuximab in Second-Line Cetuximab-Naïve Subjects With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

NCT01040832

COMPLETED Phase 1

First-in-Man, Dose-escalation Trial of C-met Kinase Inhibitor MSC2156119J in Subjects With Advanced Solid Tumors

NCT01014936

COMPLETED Phase 1

Trial of Gemcitabine With or Without MSC1936369B in Pancreatic Cancer

NCT01016483

COMPLETED

Prospective Observational Long-term Safety Registry of Multiple Sclerosis Participants Who Have Participated in Cladribine Clinical Trials

NCT01013350

COMPLETED Phase 3

The Multicenter, Open-label, Single-use Autoinjector Convenience Study

NCT00958009

TERMINATED Phase 2

Trial of Pimasertib in Hematological Malignancies

NCT00957580

TERMINATED Phase 3

STRIDE - STimulating Immune Response In aDvanced brEast Cancer

NCT00925548

COMPLETED Phase 2

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status

NCT00813943

TERMINATED Phase 2

Atacicept in Multiple Sclerosis Extension Study, Phase II

NCT00853762

TERMINATED Phase 1

Study of FOLFIRI Plus Cetuximab Plus IMO-2055 in Patients With Colorectal Cancer

NCT00719199

COMPLETED Phase 3

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status

NCT00689221

COMPLETED Phase 3

12-week Study to Evaluate RebiSmart™ Suitability for Self Injection in Relapsing Multiple Sclerosis.

NCT00735007

COMPLETED

Oocyte Cryopreservation Registry (HOPE Registry)

NCT00699400

TERMINATED Phase 2

Atacicept in Subjects With Optic Neuritis

NCT00624468

TERMINATED Phase 2

A Phase 2 Study of Atacicept in Subjects With Relapsing Multiple Sclerosis (ATAMS)

NCT00642902

COMPLETED Phase 4

Easypod United States User Trial

NCT00689260

COMPLETED Phase 2

Atacicept Phase 2/3 in Generalized Systemic Lupus Erythematosus (APRIL-SLE)

NCT00624338

TERMINATED Phase 2

The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis

NCT00573157

COMPLETED

A Multi-center, Multi-regional Observational Study to Test the Responsiveness of the Validated MusiQoL (Multiple Sclerosis International Quality of Life Questionnaire) Instrument to EDSS Status Changes in Any Form of Multiple Sclerosis (MS) in Patients With or Without Treatment

NCT00702065

COMPLETED Phase 1

Safety of Adding IMO-2055 to Erlotinib + Bevacizumab in 2nd Line Treatment for Patients With NSCLC

NCT00633529

COMPLETED Phase 2

Atacicept in Anti-Tumor Necrosis Factor Alpha-naïve Subjects With Rheumatoid Arthritis (AUGUST II)

NCT00595413

COMPLETED Phase 3

Rebif New Formulation (RNF) Quality of Life (QOL) Study

NCT00472797

COMPLETED Phase 3

Cancer Vaccine Study for Unresectable Stage III Non-small Cell Lung Cancer (START)

NCT00409188

COMPLETED Phase 2

A Phase 2 Dose-finding Study of Atacicept in Subjects With Rheumatoid Arthritis (AUGUST I)

NCT00430495

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What the Pipeline for EMD Serono Shows

According to the ClinicalTrials.gov registry, EMD Serono is linked to 71 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 48 are already marked complete, representing roughly 68% of the total.

The phase mix for EMD Serono reports 24 late-stage studies (Phase 3 and Phase 4 combined) and 40 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for EMD Serono is Patients With Solid Tumors, Either Refractory to Standard Therapy or for Which no Effective Standard Therapy is Available with 1 linked trial, and 5 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.