EMD Serono
EMD Serono sponsors 71 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 48 completed. 24 of these trials are in Phase 3-4 (later-stage) and 40 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Patients With Solid Tumors, Either Refractory to Standard Therapy or for Which no Effective Standard Therapy is Available, with 1 trials.
Trial Pipeline
71 total, page 1 of 2
Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Participant Who Participated in ADDRESS II)
NCT02070978
Sym004 in Subjects With Stage IV Non-small Cell Lung Cancer
NCT02083679
RESOunD: REbif Satisfaction On Discontinuing Oral Dimethyl Fumarate
NCT02117050
Rebif® Rebidose® Versus Rebiject II® Ease-of-Use
NCT02019550
Tecemotide Following Concurrent Chemo-radiotherapy for Non-small Cell Lung Cancer
NCT02049151
MSB0010445 and Stereotactic Body Radiation Therapy in Advanced Melanoma
NCT01973608
First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies
NCT01971515
Efficacy and Safety of Atacicept in Systemic Lupus Erythematosus
NCT01972568
Relative Bioavailability of Pimasertib in Cancer Patients
NCT01992874
Efficacy, Safety, and Tolerability of Plovamer Acetate (Pathway 1)
NCT01963611
Trial of Pimasertib With SAR245409 or Placebo in Ovarian Cancer
NCT01936363
Adherence Trial With MS LifeLines ® Services
NCT01905527
Phase II Trial of Pimasertib Versus Dacarbazine in N-Ras Mutated Cutaneous Melanoma
NCT01693068
Tecemotide (L-BLP25) in Prostate Cancer
NCT01496131
MSC2015103B in Solid Tumors
NCT01453387
Atacicept in Lupus Nephritis Patients Taking Stable Regimen of Mycophenolate Mofetil
NCT01369628
Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus
NCT01378377
Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors
NCT01390818
EMD 525797 in Subjects With Asymptomatic or Mildly Symptomatic Metastatic Castrate-resistant Prostate Cancer
NCT01360840
Saizen® Solution for Injection Adult Growth Hormone Deficiency (GHD) Immunogenicity Study
NCT01237340
Phase 2 Extension Trial in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS)
NCT01226745
Retrospective Cohort Study of Rebif® Use in Pediatric Multiple Sclerosis (MS) Subjects (REPLAY)
NCT01207648
Rebif Advanced Magnetic Resonance Imaging (MRI) and Immunology Pilot Trial
NCT01085318
First-in-Man, Dose-escalation Trial of c-Met Kinase Inhibitor EMD 1204831 in Subjects With Advanced Solid Tumors
NCT01110083
The REbif® vs Glatiramer Acetate in Relapsing Multiple Sclerosis Pharmacogenetics Trial
NCT01034579
A Multicenter, Open-label, RebiSmart™ Autoinjector Ease of Use Study
NCT01036165
EMD 1201081 in Combination With Cetuximab in Second-Line Cetuximab-Naïve Subjects With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT01040832
First-in-Man, Dose-escalation Trial of C-met Kinase Inhibitor MSC2156119J in Subjects With Advanced Solid Tumors
NCT01014936
Trial of Gemcitabine With or Without MSC1936369B in Pancreatic Cancer
NCT01016483
Prospective Observational Long-term Safety Registry of Multiple Sclerosis Participants Who Have Participated in Cladribine Clinical Trials
NCT01013350
The Multicenter, Open-label, Single-use Autoinjector Convenience Study
NCT00958009
Trial of Pimasertib in Hematological Malignancies
NCT00957580
STRIDE - STimulating Immune Response In aDvanced brEast Cancer
NCT00925548
Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status
NCT00813943
Atacicept in Multiple Sclerosis Extension Study, Phase II
NCT00853762
Study of FOLFIRI Plus Cetuximab Plus IMO-2055 in Patients With Colorectal Cancer
NCT00719199
Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status
NCT00689221
12-week Study to Evaluate RebiSmart™ Suitability for Self Injection in Relapsing Multiple Sclerosis.
NCT00735007
Oocyte Cryopreservation Registry (HOPE Registry)
NCT00699400
Atacicept in Subjects With Optic Neuritis
NCT00624468
A Phase 2 Study of Atacicept in Subjects With Relapsing Multiple Sclerosis (ATAMS)
NCT00642902
Easypod United States User Trial
NCT00689260
Atacicept Phase 2/3 in Generalized Systemic Lupus Erythematosus (APRIL-SLE)
NCT00624338
The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis
NCT00573157
A Multi-center, Multi-regional Observational Study to Test the Responsiveness of the Validated MusiQoL (Multiple Sclerosis International Quality of Life Questionnaire) Instrument to EDSS Status Changes in Any Form of Multiple Sclerosis (MS) in Patients With or Without Treatment
NCT00702065
Safety of Adding IMO-2055 to Erlotinib + Bevacizumab in 2nd Line Treatment for Patients With NSCLC
NCT00633529
Atacicept in Anti-Tumor Necrosis Factor Alpha-naïve Subjects With Rheumatoid Arthritis (AUGUST II)
NCT00595413
Rebif New Formulation (RNF) Quality of Life (QOL) Study
NCT00472797
Cancer Vaccine Study for Unresectable Stage III Non-small Cell Lung Cancer (START)
NCT00409188
A Phase 2 Dose-finding Study of Atacicept in Subjects With Rheumatoid Arthritis (AUGUST I)
NCT00430495
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 16 |
| Phase 2 | 24 |
| Phase 3 | 17 |
| Phase 4 | 7 |
What the Pipeline for EMD Serono Shows
According to the ClinicalTrials.gov registry, EMD Serono is linked to 71 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 48 are already marked complete, representing roughly 68% of the total.
The phase mix for EMD Serono reports 24 late-stage studies (Phase 3 and Phase 4 combined) and 40 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for EMD Serono is Patients With Solid Tumors, Either Refractory to Standard Therapy or for Which no Effective Standard Therapy is Available with 1 linked trial, and 5 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.