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NCT01992874 · ClinicalTrials.gov registry record · Phase 1
Relative Bioavailability of Pimasertib in Cancer Patients
A Phase 1 study, sponsored by EMD Serono.
- Completed
- Registry status
- Phase 1
- Development phase
- 38
- Enrollment target
NCT01992874: Completed Phase 1 study, sponsored by EMD Serono.
NCT01992874 is a Phase 1 study that has completed, run by EMD Serono. The registered enrollment target is 38 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (37% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01992874, a Phase 1 study, has completed, sponsored by EMD Serono.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 38 participants
- Enrollment target
Study Summary
This is a Phase 1, multi-center, open-label, single-dose, 2 period, 2 sequence cross-over trial to investigate the relative bioavailability of 2 solid oral pimasertib formulations in cancer subjects (Part A), followed by open-label pimasertib administration (Part B and trial extension phase).
Primary Outcome
Maximum observed plasma concentration (Cmax) was calculated for Part A Pimasertib 60 mg Capsule and tablet.
Interventions
- DRUG Pimasertib Capsule (Part A)
- DRUG Pimasertib Tablet (Part A)
- DRUG Pimasertib Capsule (Part B and trial extension phase)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2013-11-30 |
| Est. Completion | 2015-02-28 |
| Phase | Phase 1 |
What the finished NCT01992874 record still lists
NCT01992874 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (37% lower).
The record links to 0 conditions, and to 3 interventions - of which Pimasertib Capsule (Part A) is the first listed.
NCT01992874 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01992874 about?
NCT01992874 is a clinical study titled "Relative Bioavailability of Pimasertib in Cancer Patients". This is a Phase 1, multi-center, open-label, single-dose, 2 period, 2 sequence cross-over trial to investigate the relative bioavailability of 2 solid oral pimasertib formulations in cancer subjects (Part A), followed by open-label pimasertib administration (Part B and trial extension phase).
What is the current status of trial NCT01992874?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 38 participants. The study started on 2013-11-30. Estimated completion is 2015-02-28.
What interventions are being tested in trial NCT01992874?
The interventions under investigation include: Pimasertib Capsule (Part A) (DRUG), Pimasertib Tablet (Part A) (DRUG), Pimasertib Capsule (Part B and trial extension phase) (DRUG).
Who is sponsoring clinical trial NCT01992874?
This trial is sponsored by EMD Serono, which has 71 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01992874's enrollment target sits among peer trials
38 1197th of 2000 higher than 797 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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