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NCT00041327 · ClinicalTrials.gov registry record · Phase 2

Combination Chemotherapy Followed By Antiviral Therapy and Interferon Alfa in Treating Patients With HTLV-1-Related Adult T-Cell Leukemia/Lymphoma

A Phase 2 study, sponsored by AIDS Malignancy Consortium.

Completed
Registry status
Phase 2
Development phase
19
Enrollment target

NCT00041327 is a Phase 2 study that has completed, run by AIDS Malignancy Consortium. The registered enrollment target is 19 participants.

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The verdict

NCT00041327, a Phase 2 study, has completed, sponsored by AIDS Malignancy Consortium.

COMPLETED
Registry status
Phase 2
Development phase
19 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Antiviral therapy may kill viruses such as HTLV-1 that can cause cancer. Interferon alfa may interfere with the growth of cancer cells. Combining chemotherapy with antiviral drugs and interferon alfa may be effective in treating adult T-cell leukemia/lymphoma. PURPOSE: Phase II trial to determine the effectiveness of combination chemotherapy followed by antiviral therapy and interferon alfa in treating patients who have adult T-cell leukemia/lymphoma caused by HTLV-1.

Interventions

  • DRUG Etoposide
  • DRUG cyclophosphamide
  • BIOLOGICAL filgrastim
  • DRUG doxorubicin hydrochloride
  • BIOLOGICAL recombinant interferon alfa

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2002-10
Est. Completion 2006-12
Phase Phase 2

Sponsor

AIDS Malignancy Consortium

45 total trials

What the Registry Record Tells You About NCT00041327

The ClinicalTrials.gov registry entry for NCT00041327 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AIDS Malignancy Consortium, which has 45 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Etoposide is the first listed.

NCT00041327 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00041327 about?

NCT00041327 is a clinical study titled "Combination Chemotherapy Followed By Antiviral Therapy and Interferon Alfa in Treating Patients With HTLV-1-Related Adult T-Cell Leukemia/Lymphoma". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Antiviral therapy may kill viruses such as HTLV-1 that can cause cancer. Interferon alfa may interfere with the growth of cancer cells. Combining chemotherapy with antiviral drugs...

What is the current status of trial NCT00041327?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2002-10. Estimated completion is 2006-12.

What interventions are being tested in trial NCT00041327?

The interventions under investigation include: Etoposide (DRUG), cyclophosphamide (DRUG), filgrastim (BIOLOGICAL), doxorubicin hydrochloride (DRUG), recombinant interferon alfa (BIOLOGICAL).

Who is sponsoring clinical trial NCT00041327?

This trial is sponsored by AIDS Malignancy Consortium, which has 45 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.