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ClinicalTrials.gov 24,857 recruiting now free trial finder

Find a clinical trial that's recruiting now

Search 24,857 actively recruiting US clinical trials by condition, drug, or state, each entry links straight to its NIH ClinicalTrials.gov record so you can check eligibility and contact the study team.

24,857
trials recruiting now
14%
of all US trials open to enrollment
52
states with recruiting sites

A trial is listed as recruiting when its sponsor has marked it open to new participants on the public registry. Type a condition or drug name (for example, "breast cancer" or "pembrolizumab") to narrow the list, and add a state to find studies with a site near you. Results are ordered with the most relevant recruiting studies first; each card shows the study phase and enrollment target, and opens the full record, including eligibility criteria and contact details, on ClinicalTrials.gov.

100 trials found

Recruiting 75,000 target

Project: Every Child for Younger Patients With Cancer

Children's Oncology Group

NCT02402244

Recruiting 30,000 target

MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

Agendia

NCT03053193

Recruiting 20,000 target

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

Medtronic

NCT00271180

Recruiting NA 17,800 target

Machine Learning Prediction of Possible Central Line Associated Blood Stream Infections and Rate of Reduction

Swedish Medical Center

NCT07108660

Recruiting Phase 2 10,000 target

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

SWOG Cancer Research Network

NCT03851445

Recruiting NA 9,500 target

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

NRG Oncology

NCT05080673

Recruiting NA 8,060 target

School Screening and Telemedicine Specialty Referral to Address Childhood Hearing Loss in Rural Alaska

University of Arkansas

NCT05593484

Recruiting 8,000 target

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Stryker Instruments

NCT03072927

Recruiting Phase 3 5,951 target

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Children's Oncology Group

NCT03959085

Recruiting Phase 3 4,300 target

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

AstraZeneca

NCT05774951

Recruiting 4,000 target

The Alaska Oculocardiac Reflex Study

Alaska Blind Child Discovery

NCT04353960

Recruiting Phase 3 3,960 target

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

NRG Oncology

NCT05879926

Recruiting Phase 3 3,680 target

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

National Cancer Institute (NCI)

NCT06058377

Recruiting Phase 2 2,900 target

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

National Cancer Institute (NCI)

NCT05564377

Recruiting Phase 3 2,400 target

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

SWOG Cancer Research Network

NCT05929768

Recruiting Phase 3 2,140 target

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

Canadian Cancer Trials Group

NCT03488693

Recruiting 2,000 target

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

Wake Forest University Health Sciences

NCT06418204

Recruiting 2,000 target

Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

ECOG-ACRIN Cancer Research Group

NCT06002828

Recruiting 2,000 target

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Alliance for Clinical Trials in Oncology

NCT05334069

Recruiting NA 1,956 target

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

NRG Oncology

NCT04251052

Recruiting Phase 3 1,875 target

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

National Cancer Institute (NCI)

NCT05675410

Recruiting 1,800 target

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

Exact Sciences Corporation

NCT06401421

Recruiting Phase 3 1,780 target

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Children's Oncology Group

NCT03067181

Recruiting Phase 3 1,755 target

The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

Boehringer Ingelheim

NCT06872892

Recruiting Phase 3 1,656 target

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Children's Oncology Group

NCT06401330

Recruiting 1,600 target

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Bristol-Myers Squibb

NCT05489705

Recruiting Phase 3 1,450 target

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

ECOG-ACRIN Cancer Research Group

NCT04566328

Recruiting Phase 3 1,400 target

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

Novartis Pharmaceuticals

NCT05827081

Recruiting NA 1,312 target

Family-Based Financial Incentives Intervention for Smoking Cessation

Mayo Clinic

NCT06556433

Recruiting Phase 3 1,295 target

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Alliance for Clinical Trials in Oncology

NCT05812807

Recruiting Phase 2 1,260 target

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

BioNTech SE

NCT06712316

Recruiting Phase 3 1,210 target

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

National Cancer Institute (NCI)

NCT04267848

Recruiting Phase 3 1,123 target

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Merck Sharp & Dohme

NCT06952504

Recruiting NA 1,075 target

Efficacy-Implementation Study for PC CARES in Rural Alaska

University of Michigan

NCT06658808

Recruiting Phase 3 1,057 target

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

SWOG Cancer Research Network

NCT07018869

Recruiting Phase 3 1,018 target

A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

AstraZeneca

NCT06549595

Recruiting Phase 1 1,006 target

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT04389632

Recruiting Phase 1 960 target

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

PedAL BCU

NCT04726241

Recruiting NA 947 target

The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals

Mayo Clinic

NCT06087224

Recruiting Phase 3 920 target

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Eli Lilly and Company

NCT07174336

Recruiting Phase 2 900 target

A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study

Astellas Pharma Global Development

NCT02960022

Recruiting Phase 3 880 target

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

NRG Oncology

NCT06580314

Recruiting Phase 3 868 target

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

Merck Sharp & Dohme

NCT06077760

Recruiting Phase 2 860 target

A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Daiichi Sankyo

NCT06161025

Recruiting Phase 3 840 target

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

AstraZeneca

NCT06764875

Recruiting Phase 3 830 target

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

Canadian Cancer Trials Group

NCT06592924

Recruiting Phase 3 804 target

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

ECOG-ACRIN Cancer Research Group

NCT04423211

Recruiting NA 760 target

Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)

ECOG-ACRIN Cancer Research Group

NCT06295367

Recruiting NA 739 target

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

SWOG Cancer Research Network

NCT03723928

Recruiting Phase 3 686 target

Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

Daiichi Sankyo

NCT06899126

Recruiting Phase 3 686 target

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Merck Sharp & Dohme

NCT06459180

Recruiting Phase 3 680 target

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

Pfizer

NCT07144280

Recruiting Phase 3 675 target

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

AstraZeneca

NCT06357533

Recruiting Phase 3 668 target

S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer

SWOG Cancer Research Network

NCT04155034

Recruiting Phase 3 600 target

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Hoffmann-La Roche

NCT06793215

Recruiting Phase 1 596 target

A Study of Intravesical BCG in Combination With ALT-803 in Patients With Non-Muscle Invasive Bladder Cancer

ImmunityBio

NCT02138734

Recruiting Phase 2 590 target

A Study to Compare the Combination of BMS-986504 With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Bristol-Myers Squibb

NCT07063745

Recruiting NA 535 target

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

Alliance for Clinical Trials in Oncology

NCT07091617

Recruiting Phase 3 510 target

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

SWOG Cancer Research Network

NCT05561387

Recruiting NA 497 target

PDN Post Market, Multicenter, Prospective, Global Clinical Study

Nevro

NCT05301816

Recruiting Phase 3 491 target

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

SWOG Cancer Research Network

NCT03418961

Recruiting Phase 2 461 target

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

National Cancer Institute (NCI)

NCT04546399

Recruiting NA 450 target

More Outside Your Door: a Diet/physical Activity Intervention to Decrease Risk of Obesity in Alaska Native Preschoolers

Alaska Native Tribal Health Consortium

NCT06303544

Recruiting Phase 3 440 target

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

AstraZeneca

NCT06307665

Recruiting Phase 3 440 target

Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

Children's Oncology Group

NCT05602194

Recruiting Phase 2 430 target

Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations

Boehringer Ingelheim

NCT06581432

Recruiting NA 410 target

Mobile Health for Adherence in Breast Cancer Patients

ECOG-ACRIN Cancer Research Group

NCT06112613

Recruiting NA 400 target

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

Eastern Cooperative Oncology Group

NCT05108298

Recruiting Phase 3 400 target

A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

Celgene

NCT06911502

Recruiting NA 400 target

Jumpstarting Advance Care Planning With ANAI People

Southcentral Foundation

NCT06538493

Recruiting Phase 2 393 target

Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

Canadian Cancer Trials Group

NCT05640999

Recruiting NA 386 target

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

NRG Oncology

NCT05896189

Recruiting Phase 3 382 target

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Alliance for Clinical Trials in Oncology

NCT05677490

Recruiting Phase 2 378 target

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

SWOG Cancer Research Network

NCT06616584

Recruiting NA 368 target

Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)

Oregon Health and Science University

NCT06629610

Recruiting Phase 3 360 target

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

National Cancer Institute (NCI)

NCT05256225

Recruiting Phase 3 360 target

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Taiho Oncology

NCT07128199

Recruiting Phase 2 353 target

A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

Acrivon Therapeutics

NCT05548296

Recruiting Phase 3 348 target

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

National Cancer Institute (NCI)

NCT04530565

Recruiting Phase 2 314 target

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

National Cancer Institute (NCI)

NCT03866382

Recruiting NA 300 target

Suicide Intervention for Alaska Native Youth

RAND

NCT05360888

Recruiting Phase 3 300 target

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

National Cancer Institute (NCI)

NCT04181060

Recruiting Phase 4 300 target

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

Amgen

NCT06072482

Recruiting Phase 3 288 target

Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

ECOG-ACRIN Cancer Research Group

NCT03937635

Recruiting Phase 3 280 target

A Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With Chemotherapy Compared With Pembrolizumab in Combination With Chemotherapy in Metastatic NSCLC Patients With Non-squamous Histology Who Have Mutations and/or Co-mutations in STK11, KEAP1, or KRAS

AstraZeneca

NCT06008093

Recruiting Phase 3 280 target

Comparing Radiation Therapy to Usual Care for Patients With High-Risk Bone Asymptomatic Metastases, PREEMPT Trial

NRG Oncology

NCT06745024

Recruiting Phase 2 271 target

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

Alliance for Clinical Trials in Oncology

NCT03609216

Recruiting Phase 2 256 target

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Children's Oncology Group

NCT04322318

Recruiting Phase 2 250 target

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Merck Sharp & Dohme

NCT06979596

Recruiting Phase 3 247 target

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

National Cancer Institute (NCI)

NCT04269902

Recruiting 240 target

Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

Alliance for Clinical Trials in Oncology

NCT04242095

Recruiting 200 target

STOP AF First Post-Approval Study

Medtronic Cardiac Ablation Solutions

NCT05227053

Recruiting Phase 2 189 target

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

National Cancer Institute (NCI)

NCT05058651

Recruiting Phase 2 189 target

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

ECOG-ACRIN Cancer Research Group

NCT02734537

Recruiting Phase 2 165 target

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

National Cancer Institute (NCI)

NCT05554328

Recruiting Phase 2 160 target

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

Children's Oncology Group

NCT04684368

Recruiting Phase 2 153 target

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

National Cancer Institute (NCI)

NCT06317662

Recruiting Phase 2 152 target

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

National Cancer Institute (NCI)

NCT04858334

Recruiting Phase 2 141 target

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

SWOG Cancer Research Network

NCT05040360

Recruiting Phase 2 138 target

Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

National Cancer Institute (NCI)

NCT04402788

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Recruiting status is reported by each study's sponsor and mirrored from the public registry. Always confirm current eligibility and status on ClinicalTrials.gov before contacting a study.

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