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NCT05548296 · ClinicalTrials.gov registry record · Phase 2
A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma
A Phase 2 study of Endometrial Adenocarcinoma, sponsored by Acrivon Therapeutics.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 353
- Enrollment target
- 20
- Study locations
NCT05548296 is a Phase 2 study of Endometrial Adenocarcinoma that is actively recruiting participants, run by Acrivon Therapeutics. The registered enrollment target is 353 participants, above the 313-participant average among 13 other Endometrial Adenocarcinoma trials with a reported enrollment target (13% higher). The trial reports 20 study locations across 9 states.
The verdict
NCT05548296, a Phase 2 study of Endometrial Adenocarcinoma, is actively recruiting participants, sponsored by Acrivon Therapeutics.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 353 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial cancer.
Conditions Studied
Interventions
- DRUG Gemcitabine
- DRUG ACR-368
- DIAGNOSTIC_TEST OncoSignature
Study Locations (20)
California
- City of Hope National Medical Center - Duarte
- UC San Diego Moores Cancer Center - La Jolla
- USC/Norris Comprehensive Cancer Center - Los Angeles
- Cedars Sinai Medical Center - Los Angeles
- Hoag Cancer Center - Newport Beach
- UC Irvine Health - Orange
- Stanford Cancer Center - Palo Alto
- University of California, Davis Comprehensive Cancer Center - Sacramento
- University of California Los Angeles (UCLA) - Santa Monica
Arizona
- HonorHealth - Phoenix
- Arizona Oncology Associate, PC- HOPE - Tucson
Florida
- Florida Gynecologic Oncology/Regional Cancer Center - Fort Myers
- Mount Sinai Comprehensive Cancer Center - Miami Beach
Georgia
- Emory University - Atlanta
- Northeast Georgia Medical Center - Gainesville
Alabama
- University of South Alabama Mitchell Cancer Institute - Mobile
Alaska
- Alaska Women's Cancer Center - Anchorage
Arkansas
- University of Arkansas for Medical Sciences - Little Rock
Colorado
- University of Colorado - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 353 participants |
| Start Date | 2022-08-29 |
| Est. Completion | 2027-04-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05548296
The ClinicalTrials.gov registry entry for NCT05548296 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 353 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 313-participant average among 13 other Endometrial Adenocarcinoma trials with a reported enrollment target (13% higher). The listed sponsor is Acrivon Therapeutics, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Endometrial Adenocarcinoma appearing as the primary indexed condition, and to 3 interventions - of which Gemcitabine is the first listed.
NCT05548296 reports 20 study locations spanning 9 distinct geographic areas - top geographies include California, Arizona, Florida.
Frequently Asked Questions
What is clinical trial NCT05548296 about?
NCT05548296 is a clinical study titled "A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma". This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitization in participants with endometrial cancer.
What is the current status of trial NCT05548296?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 353 participants. The study started on 2022-08-29. Estimated completion is 2027-04-30.
What conditions does trial NCT05548296 study?
This clinical trial studies the following conditions: Endometrial Adenocarcinoma.
What interventions are being tested in trial NCT05548296?
The interventions under investigation include: Gemcitabine (DRUG), ACR-368 (DRUG), OncoSignature (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05548296?
This trial is sponsored by Acrivon Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05548296 being conducted?
This trial has 20 study locations across Alabama, Alaska, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.