Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
X-Linked Retinitis Pigmentosa: early-phase trial registry
A small indexed set (9 trials) with no open enrollment listed right now.
Corpus placement: #1,916 of 28,707 conditions by registered trial count.
9 US clinical trials · none currently recruiting · #1,916 of 28,707 conditions by registered trial count
X-Linked Retinitis Pigmentosa: 9 US clinical trials tracked, none currently recruiting.
X-Linked Retinitis Pigmentosa is the subject of 9 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 2 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Janssen Research & Development, running 4 of these trials.
Enrollment posture brief
Registry condition x-linked-retinitis-pigmentosa
OPEN 0 | RECR 0% | LATE 2 | EARLY 6 | RANK #1916 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)
X-Linked Retinitis Pigmentosa has no open enrollment in this registry pull (9 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for X-Linked Retinitis Pigmentosa on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
X-Linked Retinitis Pigmentosa is recruiting below its size-band peers.
0 of 9 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
One sponsor concentrates X-Linked Retinitis Pigmentosa research.
Janssen Research & Development accounts for 4 of 9 trials (44.4%). 4 distinct sponsors appear on at least one study for this condition label.
-
Most X-Linked Retinitis Pigmentosa trials plan to enrol fewer than 100 people.
Median target enrolment is 42 among the 9 trials that report a genuine target (sentinel values excluded). 8 of those (88.9%) plan for fewer than 100 participants.
-
X-Linked Retinitis Pigmentosa research is mostly interventional.
8 interventional and 1 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Indexed trials (enrollment closed)
9 total, page 1 of 1
Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Janssen Research & Development
NCT04794101
A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRP
Beacon Therapeutics
NCT04850118
Safety and Efficacy of rAAV2tYF-GRK1-RPGR in Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations
Beacon Therapeutics
NCT03316560
A Follow-on Study for Second-Eye Treatment for Participants Previously Treated With Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP)
Janssen Research & Development
NCT06646289
4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)
4D Molecular Therapeutics
NCT04517149
A Study Comparing Two Doses of AGTC-501 in Male Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (SKYLINE)
Beacon Therapeutics
NCT06333249
Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene
Janssen Research & Development
NCT04671433
A Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Using BIIB112
Biogen
NCT03116113
Long-term Follow-up Gene Therapy Study for RPGR- XLRP
Janssen Research & Development
NCT04312672
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 3 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on X-Linked Retinitis Pigmentosa records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on X-Linked Retinitis Pigmentosa trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this X-Linked Retinitis Pigmentosa page
9 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- No X-Linked Retinitis Pigmentosa trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
- Janssen Research & Development sponsors the most X-Linked Retinitis Pigmentosa trials on record, review their full trial history before evaluating a specific study. See Janssen Research & Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This X-Linked Retinitis Pigmentosa condition card totals 9 registered trials; most-linked intervention AAV5-hRKp.RPGR; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.