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2026 data Public-data reference. official source

Weight Gain

Open-data reference.

39 US clinical trials · 12 currently recruiting

Active & Recent Trials

RECRUITING NA 570 participants

Grocery Delivery and Healthy Weight Gain Among Low-income Pregnant Young Women

University of Michigan

NCT05000645

RECRUITING NA 360 participants

Testing Responses of Young Adults to Intervention Messages for Promoting Physical Activity Trial

University of Michigan

NCT05794178

RECRUITING Phase 3 300 participants

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

Eli Lilly and Company

NCT06439277

RECRUITING NA 250 participants

The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer

Johns Hopkins University

NCT05780814

RECRUITING NA 150 participants

The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)

Arkansas Children's Hospital Research Institute

NCT05992688

RECRUITING Phase 2 144 participants

A Novel Obesity Prevention Program for High-Risk Infants in Primary Care

Children's Hospital Medical Center, Cincinnati

NCT06028113

RECRUITING Phase 2 120 participants

Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy Volunteers

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05652478

RECRUITING NA 110 participants

Time Restricted Eating for WeIght LoSs MainTenance-2

NYU Langone Health

NCT07190170

RECRUITING NA 46 participants

Exercise Effects on Adipose Tissue Structure and Function

University of Michigan

NCT04812314

RECRUITING Phase 2 30 participants

Incretin Microdosing for Cardiometabolic Health in People With HIV

The University of Texas Health Science Center, Houston

NCT07325500

RECRUITING NA 20 participants

Sleep and Metabolism

Oregon Health and Science University

NCT05775627

RECRUITING NA 15 participants

Exercise, Brain Activity, and Weight Maintenance

Joslin Diabetes Center

NCT06511310

ACTIVE NOT RECRUITING NA 70 participants

Comparing Reduction With ESD- Versus APC-TORe

Stephen Firkins

NCT06131281

COMPLETED NA 2,184 participants

Effects of Sugary Drinks Counter-marketing Messages

Stanford University

NCT05953194

COMPLETED NA 1,067 participants

Implementing Effective, Collaborative Care for Schizophrenia (EQUIP-2)

VA Office of Research and Development

NCT00137280

COMPLETED NA 599 participants

Study of Novel Approaches for Prevention

Wake Forest University

NCT01183689

COMPLETED NA 489 participants

The GEM (Goals for Eating and Moving) Study

NYU Langone Health

NCT03006328

COMPLETED NA 430 participants

Gestational Weight Gain and Postpartum Weight Loss in Active Duty Women (Moms Fit 2 Fight)

University of Tennessee

NCT03057808

COMPLETED NA 281 participants

Maternal-Offspring Metabolics:Family Intervention Trial

Northwestern University

NCT01631747

COMPLETED NA 176 participants

Whole Body Vibration Training for Healthy Body Composition in Young Adults

Oregon Health and Science University

NCT02134275

COMPLETED NA 160 participants

Neurobehavioral Plasticity to Regular Sugar-Sweetened Beverage Intake: An fMRI Experiment

University of North Carolina, Chapel Hill

NCT03490734

COMPLETED NA 142 participants

Healthy Motivations for Moms-to-be Study

University of South Carolina

NCT03063528

COMPLETED 110 participants

Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen

Thomas Jefferson University

NCT03646370

COMPLETED 100 participants

The Effects of Overfeeding on Obesity-Prone (OP) and Obesity-Resistant (OR) Women

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00072917

COMPLETED Phase 1 96 participants

Reducing Antipsychotic-Induced Weight Gain in Children With Metformin

Nationwide Children's Hospital

NCT01231074

COMPLETED NA 55 participants

Cardiovascular Health in Postpartum Women Diagnosed With Excessive Gestational Weight Gain

Stanford University

NCT02142452

COMPLETED NA 52 participants

Weight Gain Prevention

The Miriam Hospital

NCT00606840

COMPLETED NA 48 participants

Eating Mindfully to Prevent Weight Regain

University of Utah

NCT04847843

COMPLETED NA 44 participants

Effect of Milk Warming on the Very Low Birth Weight Infant

University of Oklahoma

NCT04282655

COMPLETED NA 33 participants

Development of Fluid Intake App for Management of Fluid Intake During Hemodialysis , Full Scale Trial

Wake Forest University Health Sciences

NCT04194164

COMPLETED NA 32 participants

Body Composition Changes During Overfeeding Plus Resistance Training

Texas Tech University

NCT04069351

COMPLETED 27 participants

Role Of Metabolic Adaptation In Weight Regain

Pennington Biomedical Research Center

NCT05766358

COMPLETED NA 23 participants

Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness

Stanford University

NCT03935854

COMPLETED Phase 1 20 participants

Lorcaserin for Preventing Weight Gain Among Smokers

Mayo Clinic

NCT02393547

COMPLETED NA 18 participants

Preventing Weight Gain in African American Reproductive-Aged Women

Washington University School of Medicine

NCT02416921

COMPLETED NA 18 participants

A Trial of Lifestyle Interventions to Control Weight After Bariatric Surgery

Beth Israel Deaconess Medical Center

NCT02603601

COMPLETED 15 participants

Effects of Antipsychotic Medications on Energy Intake and Expenditure

Washington University School of Medicine

NCT00836251

COMPLETED Phase 2 9 participants

Strategies to Reduce Antipsychotic-Associated Weight Gain in Youth

University of North Carolina, Chapel Hill

NCT00617240

COMPLETED 4 participants

Horton & Maizy Pilot Study for Resistant to Starch

Pennington Biomedical Research Center

NCT01338571

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 4
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Weight Gain Trial Landscape

ClinicalTrials.gov lists 39 US studies indexed under Weight Gain, and 12 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Weight Gain shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Weight Gain is led by University of Michigan with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 39 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Weight Gain?

PlainTrial tracks 39 US clinical trials for Weight Gain, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Weight Gain?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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