Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Vaso-occlusive Crisis: full-pipeline trial registry
2 of 5 indexed Vaso-occlusive Crisis trials are currently recruiting.
Corpus placement: #3,391 of 28,707 conditions by registered trial count.
5 US clinical trials · 2 currently recruiting · #3,391 of 28,707 conditions by registered trial count
Vaso-occlusive Crisis: 5 US clinical trials tracked, 2 recruiting.
Vaso-occlusive Crisis is the subject of 5 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is St. Jude Children's Research Hospital, running 1 of these trials.
Enrollment posture brief
Registry condition vaso-occlusive-crisis
OPEN 2 | RECR 40% | LATE 2 | EARLY 2 | RANK #3391 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Achondroplasia (40% recruiting · 10 trials)
Vaso-occlusive Crisis lists 2 open slots (40% of 5 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Vaso-occlusive Crisis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Vaso-occlusive Crisis is recruiting below its size-band peers.
2 of 5 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Vaso-occlusive Crisis research.
St. Jude Children's Research Hospital accounts for 1 of 5 trials (20%). 5 distinct sponsors appear on at least one study for this condition label.
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Most Vaso-occlusive Crisis trials plan to enrol fewer than 100 people.
Median target enrolment is 34 among the 5 trials that report a genuine target (sentinel values excluded). 4 of those (80%) plan for fewer than 100 participants.
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Vaso-occlusive Crisis research is mostly interventional.
5 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
5 total, page 1 of 1
Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease
St. Jude Children's Research Hospital
NCT03353584
Oral Ketamine for Treatment of Vaso-Occlusive Pain
Boston Children's Hospital
NCT05378555
A Study to Assess the Safety and Efficacy of Inclacumab in Participants With Sickle Cell Disease Experiencing Vaso-occlusive Crises
Pfizer
NCT04935879
Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus Placebo
Duke University
NCT01419977
Nitrous Oxide Analgesia Vaso-occlusive Crisis
Columbia University
NCT01891812
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Vaso-occlusive Crisis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Vaso-occlusive Crisis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Vaso-occlusive Crisis page
5 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Vaso-occlusive Crisis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- St. Jude Children's Research Hospital sponsors the most Vaso-occlusive Crisis trials on record, review their full trial history before evaluating a specific study. See St. Jude Children's Research Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Vaso-occlusive Crisis condition card totals 5 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.