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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Urolithiasis: early-phase trial registry

5 of 12 indexed Urolithiasis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 5 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Urolithiasis: 12 US clinical trials tracked, 5 recruiting.

Urolithiasis is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of Alabama at Birmingham, running 3 of these trials.

Enrollment posture brief

Registry condition urolithiasis

OPEN 5 | RECR 42% | LATE 0 | EARLY 2 | RANK #1429 | SPON 3

Nearest open-share peer: Adiposity (42% recruiting · 12 trials)

Urolithiasis (this)42%Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Urolithiasis

Urolithiasis lists 5 open slots (42% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Urolithiasis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Urolithiasis is recruiting below its size-band peers.

    5 of 12 indexed trials (41.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Urolithiasis research.

    University of Alabama at Birmingham accounts for 3 of 12 trials (25%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Typical Urolithiasis enrolment sits around 80 participants.

    Median target enrolment is 80 among the 12 trials that report a genuine target (sentinel values excluded). 7 of those (58.3%) plan for fewer than 100 participants.

  4. Urolithiasis research is mostly interventional.

    11 interventional and 1 observational studies make up this index (91.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21

Open and recent trials

12 total, page 1 of 1

RECRUITING NA 126 participants

Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure

Northwestern University

NCT05100017

RECRUITING NA 80 participants

Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease

University of Alabama at Birmingham

NCT06989320

RECRUITING NA 80 participants

Gut Oxalate Absorption in Calcium Oxalate Stone Disease

University of Alabama at Birmingham

NCT06331546

RECRUITING Phase 1 80 participants

Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease

University of Texas Southwestern Medical Center

NCT06158620

RECRUITING NA 40 participants

O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease

University of Alabama at Birmingham

NCT06330246

ACTIVE NOT RECRUITING 3,000 participants

A Retrospective, Multi-center Real-world Study of Steerable Ureteroscopic Renal Evacuation (SURE) Procedure With the CVAC® System

Calyxo

NCT07225933

ACTIVE NOT RECRUITING NA 370 participants

Ultrasound Imaging of Kidney Stones and Lithotripsy

University of Washington

NCT02214836

ACTIVE NOT RECRUITING NA 116 participants

SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)

SonoMotion

NCT05701098

COMPLETED Phase 2 239 participants

Study of Silodosin to Facilitate Passage of Urinary Stones

Watson Pharmaceuticals

NCT01144949

COMPLETED NA 31 participants

Feasibility of Using sipIT Tools to Increase Compliance With Fluid Consumption Guidelines in Urolithiasis-Prone Subjects

Penn State University

NCT03787615

COMPLETED NA 18 participants

Standard vs Mini-PCNL for the Treatment of Stone Disease

The Cleveland Clinic

NCT04069013

COMPLETED NA 12 participants

Effect of Diet Orange Soda on Urinary Lithogenicity

VA New York Harbor Healthcare System

NCT01330940

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1

Named interventions

Most-linked intervention names on Urolithiasis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

PCNL Procedure
1 trials
silodosin Drug
1 trials
sipIT tools Device
1 trials
Orange soda Dietary supplement
1 trials
Flexible AND Navigational Ureteral Access Sheath (fans) IN Flexible Ureteroscopy (furs) Device
1 trials
Cvac® System Device
1 trials
Verasonics Data Acquisition System (VDAS) Device
1 trials
oral diclofenac Drug
1 trials

US sites by state

Facility locations filed on Urolithiasis trials. A trial with sites in several states counts in each.

Texas 4 trials
Alabama 4 trials
California 3 trials
Washington 2 trials
Pennsylvania 2 trials
Ohio 2 trials
New York 2 trials
Illinois 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Urolithiasis page

12 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Urolithiasis condition card totals 12 registered trials; most-linked intervention PCNL; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.