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NCT06033274 · ClinicalTrials.gov registry record
Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment
A clinical trial of Tricuspid Regurgitation, sponsored by Montefiore Medical Center.
- Recruiting
- Registry status
- 800
- Enrollment target
- 20
- Study locations
NCT06033274: Recruiting study of Tricuspid Regurgitation, sponsored by Montefiore Medical Center.
NCT06033274 is a study of Tricuspid Regurgitation that is actively recruiting participants, run by Montefiore Medical Center. The registered enrollment target is 800 participants, above the 489-participant average among 17 other Tricuspid Regurgitation trials with a reported enrollment target (64% higher). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06033274, a study of Tricuspid Regurgitation, is actively recruiting participants, sponsored by Montefiore Medical Center.
- RECRUITING
- Registry status
- 800 participants
- Enrollment target
- 20
- Study locations
Study Summary
The field of transcatheter tricuspid valve replacement (TTVR) is rapidly emerging and data on this topic are scarce. Particularly, little is known about which patients are at greatest risk of procedural complications, such as the timing and onset of conduction disturbances necessitating permanent pacemaker implantation, and how such patients are managed. On this background, the TRIPLACE Registry - an investigator-initiated global multicenter registry - is aimed at better understanding the safety and efficacy of orthotopic TTVR.
Primary Outcome
Freedom from device-related complications will be determined by assessing the number of participants with procedural, peri-procedural and device-related complications
Conditions Studied
Interventions
- DEVICE Transcatheter Tricuspid Valve Replacement
Study Locations (20)
Other
- Rigshospitalet, Copenhagen University Hospital - Copenhagen
- Centre Hospitalier Universitaire de Lille - Lille
- Clinique Pasteur Toulouse - Toulouse
- Heart and Diabetes Centre, North Rhine-Westphalia (NRW), Ruhr-University - Bad Oeynhausen
- Heart Center Cologne, University of Cologne - Cologne
- Cardiovascular Center (CVC) Frankfurt, Division of Cardiology - Frankfurt
- University Heart and Vascular Center, Department of Cardiology - Hamburg
- University Heart Center, Schleswig-Holstein University - Lübeck
- Medical Clinic and Polyclinic, University Hospital of Munich (LMU Klinikum) - Munich
- San Raffaele University Hospital - Milan
- Centro Cardiologico Monzino IRCCS - Milan
New York
- Columbia University Irving Medical Center - New York
- Montefiore Medical Center - The Bronx
Arizona
- Arizona Heart Hospital (Biltmore Cardiology) - Phoenix
Ohio
- Cleveland Clinic - Cleveland
Oregon
- Oregon Health & Science University - Portland
British Columbia
- St. Paul's Hospital - Vancouver
Ontario
- St Michael's Hospital, University of Toronto - Toronto
Quebec
- Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada - Québec
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 800 participants |
| Start Date | 2023-10-05 |
| Est. Completion | 2026-08 |
What NCT06033274 shows while recruiting
NCT06033274 is an observational study that tracks outcomes without assigning an intervention. The registered 800 participants enrollment target is mid-sized for trials with a published cap, above the 489-participant average among 17 other Tricuspid Regurgitation trials with a reported enrollment target (64% higher).
The record links to 1 condition, with Tricuspid Regurgitation appearing as the primary indexed condition, and to 1 intervention - of which Transcatheter Tricuspid Valve Replacement is the first listed.
NCT06033274 names 20 study sites across 9 states, led by Other, New York, Arizona.
Frequently Asked Questions
What is clinical trial NCT06033274 about?
NCT06033274 is a clinical study titled "Global Multicenter Registry on Transcatheter TRIcuspid Valve RePLACEment". The field of transcatheter tricuspid valve replacement (TTVR) is rapidly emerging and data on this topic are scarce. Particularly, little is known about which patients are at greatest risk of procedural complications, such as the timing and onset of conduction disturbances necessitating permanent pa...
What is the current status of trial NCT06033274?
This trial is currently recruiting. The enrollment target is 800 participants. The study started on 2023-10-05. Estimated completion is 2026-08.
What conditions does trial NCT06033274 study?
This clinical trial studies the following conditions: Tricuspid Regurgitation.
What interventions are being tested in trial NCT06033274?
The interventions under investigation include: Transcatheter Tricuspid Valve Replacement (DEVICE).
Who is sponsoring clinical trial NCT06033274?
This trial is sponsored by Montefiore Medical Center, which has 345 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06033274 being conducted?
This trial has 20 study locations across Arizona, New York, Ohio, Oregon, British Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tricuspid Regurgitation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06033274's enrollment target sits among peer trials
800 5th of 17 higher than 13 of 17 other Tricuspid Regurgitation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tricuspid Regurgitation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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