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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Tic Disorders: early-phase trial registry

5 of 10 indexed Tic Disorders trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 5 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Tic Disorders: 10 US clinical trials tracked, 5 recruiting.

Tic Disorders is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Neurological Disorders and Stroke (NINDS), running 3 of these trials.

Enrollment posture brief

Registry condition tic-disorders

OPEN 5 | RECR 50% | LATE 0 | EARLY 1 | RANK #1724 | SPON 3

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Acute Leukemia of Ambiguous 80%Tic Disorders (this)50%Achondroplasia40%Accelerated Phase Chronic My20%Accidental Fall20%
Open-enrollment share among volume-matched conditions near Tic Disorders

Tic Disorders lists 5 open slots (50% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Tic Disorders on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Tic Disorders is recruiting above its size-band peers.

    5 of 10 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Tic Disorders research.

    National Institute of Neurological Disorders and Stroke (NINDS) accounts for 3 of 10 trials (30%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Typical Tic Disorders enrolment sits around 120 participants.

    Median target enrolment is 120 among the 10 trials that report a genuine target (sentinel values excluded). 5 of those (50%) plan for fewer than 100 participants.

  4. Tic Disorders research is mostly interventional.

    7 interventional and 3 observational studies make up this index (70% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21

Open and recent trials

10 total, page 1 of 1

RECRUITING NA 1,000 participants

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

Massachusetts Eye and Ear Infirmary

NCT05317390

RECRUITING NA 200 participants

Comprehensive Behavioral Intervention for Tics

University of Miami

NCT05370391

RECRUITING NA 150 participants

Remote Delivery of a Mindfulness-based Intervention for Tics

Johns Hopkins University

NCT06408662

RECRUITING NA 30 participants

Trajectories of Change in Tourette Syndrome

University of Minnesota

NCT06679790

RECRUITING NA 12 participants

Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder

University of Utah

NCT06385535

COMPLETED 300 participants

Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00001667

COMPLETED Phase 2 120 participants

Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children

Tourette Association of America

NCT00218777

COMPLETED 54 participants

Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00056420

COMPLETED NA 50 participants

Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics

University of Minnesota

NCT04578912

COMPLETED 42 participants

Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder

National Institute of Neurological Disorders and Stroke (NINDS)

NCT00081419

Phase Distribution

PhaseTrial count
Phase 2 1

Named interventions

Most-linked intervention names on Tic Disorders records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Comprehensive Behavioral Intervention for Tics (CBIT) Behavioral
2 trials
Comprehensive Behavioral Intervention for Tics Behavioral
2 trials
Continuous Theta Burst Stimulation (cTBS) Device
1 trials
DystoniaNet-based diagnosis of isolated dystonia Diagnostic test
1 trials
Habit Reversal Training (HRT) Behavioral
1 trials
psychoeducation with relaxation and supportive therapy (PRST) Other
1 trials
mindfulness-based intervention for tics (MBIT) Other
1 trials
Repetitive Transcranial Magnetic Stimulation (rTMS) Device
1 trials

US sites by state

Facility locations filed on Tic Disorders trials. A trial with sites in several states counts in each.

Maryland 5 trials
Minnesota 2 trials
Wisconsin 1 trials
Utah 1 trials
Massachusetts 1 trials
Florida 1 trials
California 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Tic Disorders page

10 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Tic Disorders condition card totals 10 registered trials; most-linked intervention Comprehensive Behavioral Intervention for Tics (CBIT); top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.