Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Thyroid Eye Disease clinical trials
5 of 16 indexed Thyroid Eye Disease trials are currently recruiting.
16 US clinical trials · 5 currently recruiting
Thyroid Eye Disease is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Viridian Therapeutics, running 4 of these trials.
The research picture
Thyroid Eye Disease has 16 registered US clinical trials, 5 of them open to new participants right now, about 31% of the total.
- 5
- recruiting participants now
- 31%
- of trials open to enrollment
- 9
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Viridian Therapeutics
Active & Recent Trials
16 total, page 1 of 1
The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction
Walter Reed National Military Medical Center
NCT06275373
A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
Amgen
NCT06401044
A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease
Tourmaline Bio
NCT06088979
Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
Sling Therapeutics
NCT06112340
Evaluation of K9 in Subjects With Thyroid Eye Disease (TED)
Peter Timoney
NCT06467435
An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Chronic Thyroid Eye Disease (TED)
Viridian Therapeutics
NCT06625398
Extension Study to Assess Batoclimab in Participants With Thyroid Eye Disease
Immunovant Sciences
NCT05517447
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease
Hoffmann-La Roche
NCT05987423
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease
Hoffmann-La Roche
NCT06106828
An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)
Viridian Therapeutics
NCT06625411
Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease
Immunovant Sciences
NCT05524571
A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)
Sling Therapeutics
NCT05276063
A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease
Amgen
NCT06248619
A Safety, Tolerability and Pharmacokinetics Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)
Viridian Therapeutics
NCT07155668
A Safety, Tolerability and Efficacy Study of Veligrotug (VRDN 001) in Healthy Volunteers and Participants With Thyroid Eye Disease (TED) ( THRIVE )
Viridian Therapeutics
NCT05176639
Anti-VEGF Therapy for Acute Thyroid Eye Disease
Massachusetts Eye and Ear Infirmary
NCT04311606
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 4 |
| Phase 3 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Thyroid Eye Disease Trial Landscape
16 indexed Thyroid Eye Disease studies · 5 recruiting (31%).
Phase mix: 9 late (III/IV) vs 6 early (I/II).
Top sponsor: Viridian Therapeutics (4 trials), 8 others listed. 16 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Thyroid Eye Disease?
PlainTrial tracks 16 US clinical trials for Thyroid Eye Disease, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Thyroid Eye Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.