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ClinicalTrials.gov 5 recruiting now official registry

Thyroid Eye Disease clinical trials

5 of 16 indexed Thyroid Eye Disease trials are currently recruiting.

16 US clinical trials · 5 currently recruiting

Thyroid Eye Disease is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Viridian Therapeutics, running 4 of these trials.

The research picture

Thyroid Eye Disease has 16 registered US clinical trials, 5 of them open to new participants right now, about 31% of the total.

5
recruiting participants now
31%
of trials open to enrollment
9
in Phase 3–4 (later-stage)
4
top sponsor: Viridian Therapeutics
Phase 12Phase 24Phase 39

Active & Recent Trials

16 total, page 1 of 1

RECRUITING 100 participants

The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

Walter Reed National Military Medical Center

NCT06275373

RECRUITING Phase 1 88 participants

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

Amgen

NCT06401044

RECRUITING Phase 2 81 participants

A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease

Tourmaline Bio

NCT06088979

RECRUITING Phase 2 75 participants

Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Sling Therapeutics

NCT06112340

RECRUITING Phase 1 13 participants

Evaluation of K9 in Subjects With Thyroid Eye Disease (TED)

Peter Timoney

NCT06467435

ACTIVE NOT RECRUITING Phase 3 195 participants

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Chronic Thyroid Eye Disease (TED)

Viridian Therapeutics

NCT06625398

ACTIVE NOT RECRUITING Phase 3 180 participants

Extension Study to Assess Batoclimab in Participants With Thyroid Eye Disease

Immunovant Sciences

NCT05517447

ACTIVE NOT RECRUITING Phase 3 131 participants

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

Hoffmann-La Roche

NCT05987423

ACTIVE NOT RECRUITING Phase 3 127 participants

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

Hoffmann-La Roche

NCT06106828

ACTIVE NOT RECRUITING Phase 3 117 participants

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)

Viridian Therapeutics

NCT06625411

ACTIVE NOT RECRUITING Phase 3 100 participants

Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease

Immunovant Sciences

NCT05524571

ACTIVE NOT RECRUITING Phase 2 90 participants

A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Sling Therapeutics

NCT05276063

ACTIVE NOT RECRUITING Phase 3 89 participants

A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease

Amgen

NCT06248619

ACTIVE NOT RECRUITING Phase 3 87 participants

A Safety, Tolerability and Pharmacokinetics Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)

Viridian Therapeutics

NCT07155668

COMPLETED Phase 3 113 participants

A Safety, Tolerability and Efficacy Study of Veligrotug (VRDN 001) in Healthy Volunteers and Participants With Thyroid Eye Disease (TED) ( THRIVE )

Viridian Therapeutics

NCT05176639

COMPLETED Phase 2 11 participants

Anti-VEGF Therapy for Acute Thyroid Eye Disease

Massachusetts Eye and Ear Infirmary

NCT04311606

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4
Phase 3 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Thyroid Eye Disease Trial Landscape

16 indexed Thyroid Eye Disease studies · 5 recruiting (31%).

Phase mix: 9 late (III/IV) vs 6 early (I/II).

Top sponsor: Viridian Therapeutics (4 trials), 8 others listed. 16 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Thyroid Eye Disease?

PlainTrial tracks 16 US clinical trials for Thyroid Eye Disease, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Thyroid Eye Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.