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ClinicalTrials.gov 5 recruiting now full pipeline small index

Thyroid Eye Disease: full-pipeline trial registry

5 of 16 indexed Thyroid Eye Disease trials are currently recruiting.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 5 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Thyroid Eye Disease: 16 US clinical trials tracked, 5 recruiting.

Thyroid Eye Disease is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Viridian Therapeutics, running 4 of these trials.

Enrollment posture brief

Registry condition thyroid-eye-disease

OPEN 5 | RECR 31% | LATE 9 | EARLY 6 | RANK #1060 | SPON 4

Nearest open-share peer: Aortic Valve Disease (31% recruiting · 16 trials)

Adolescent62.5%Alcohol Intoxication56.3%AL Amyloidosis43.8%Thyroid Eye Disease (this)31%Allergy18.8%
Open-enrollment share among volume-matched conditions near Thyroid Eye Disease

Thyroid Eye Disease lists 5 open slots (31% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Thyroid Eye Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Thyroid Eye Disease is recruiting below its size-band peers.

    5 of 16 indexed trials (31.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Thyroid Eye Disease research.

    Viridian Therapeutics accounts for 4 of 16 trials (25%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Typical Thyroid Eye Disease enrolment sits around 100 participants.

    Median target enrolment is 100 among the 16 trials that report a genuine target (sentinel values excluded). 8 of those (50%) plan for fewer than 100 participants.

  4. Thyroid Eye Disease research is mostly interventional.

    15 interventional and 1 observational studies make up this index (93.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 24Phase 39

Open and recent trials

16 total, page 1 of 1

RECRUITING 100 participants

The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

Walter Reed National Military Medical Center

NCT06275373

RECRUITING Phase 1 88 participants

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

Amgen

NCT06401044

RECRUITING Phase 2 81 participants

A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease

Tourmaline Bio

NCT06088979

RECRUITING Phase 2 75 participants

Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Sling Therapeutics

NCT06112340

RECRUITING Phase 1 13 participants

Evaluation of K9 in Subjects With Thyroid Eye Disease (TED)

Peter Timoney

NCT06467435

ACTIVE NOT RECRUITING Phase 3 195 participants

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Chronic Thyroid Eye Disease (TED)

Viridian Therapeutics

NCT06625398

ACTIVE NOT RECRUITING Phase 3 180 participants

Extension Study to Assess Batoclimab in Participants With Thyroid Eye Disease

Immunovant Sciences

NCT05517447

ACTIVE NOT RECRUITING Phase 3 131 participants

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

Hoffmann-La Roche

NCT05987423

ACTIVE NOT RECRUITING Phase 3 127 participants

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Thyroid Eye Disease

Hoffmann-La Roche

NCT06106828

ACTIVE NOT RECRUITING Phase 3 117 participants

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)

Viridian Therapeutics

NCT06625411

ACTIVE NOT RECRUITING Phase 3 100 participants

Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease

Immunovant Sciences

NCT05524571

ACTIVE NOT RECRUITING Phase 2 90 participants

A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Sling Therapeutics

NCT05276063

ACTIVE NOT RECRUITING Phase 3 89 participants

A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease

Amgen

NCT06248619

ACTIVE NOT RECRUITING Phase 3 87 participants

A Safety, Tolerability and Pharmacokinetics Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)

Viridian Therapeutics

NCT07155668

COMPLETED Phase 3 113 participants

A Safety, Tolerability and Efficacy Study of Veligrotug (VRDN 001) in Healthy Volunteers and Participants With Thyroid Eye Disease (TED) ( THRIVE )

Viridian Therapeutics

NCT05176639

COMPLETED Phase 2 11 participants

Anti-VEGF Therapy for Acute Thyroid Eye Disease

Massachusetts Eye and Ear Infirmary

NCT04311606

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 4
Phase 3 9

Named interventions

Most-linked intervention names on Thyroid Eye Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
6 trials
VRDN-003 Drug
3 trials
Placebo Other
3 trials
Batoclimab Drug
2 trials
Satralizumab Drug
2 trials
VRDN-001 Placebo Drug
1 trials
VRDN-001 Phase 3 Cohort (THRIVE) Drug
1 trials
Sub-tenon injection of hyaluronidase (HA) alone Drug
1 trials

US sites by state

Facility locations filed on Thyroid Eye Disease trials. A trial with sites in several states counts in each.

California 10 trials
Florida 9 trials
Texas 8 trials
Michigan 8 trials
Illinois 8 trials
West Virginia 7 trials
Massachusetts 6 trials
Nevada 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Thyroid Eye Disease page

16 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Thyroid Eye Disease condition card totals 16 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.