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RECRUITING Phase 2

A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease

NCT06088979 · View on ClinicalTrials.gov ↗

Study Summary

Phase 2b trial of TOUR006 in Thyroid Eye Disease (TED) to evaluate 20mg and 50mg doses against placebo given by a subcutaneous injection every eight weeks to TED patients who are in the active inflammatory phase of disease.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG TOUR006 - 20 MG
  • DRUG TOUR006 - 50 MG

Study Locations (20)

California

  • Headlands Research - AMCR - Site 840-131 — Escondido
  • Foothill Eye Institute - Site 840-116 — Pasadena
  • University of California Davis Eye Center - Site 840-119 — Sacramento
  • Cockerham Eye Consultants - Site 840-114 — San Diego
  • The Pacific Center for Oculofacial and Aesthetic Plastic Surgery - Site 840-122 — San Francisco

Florida

  • Bascom Palmer Eye Institute - Site 840-115 — Miami
  • Cordova Research Institute - Site 840-103 — Miami
  • Aran Eye Associate — Sweetwater

Michigan

  • W.K. Kellogg Eye Center - Site 840-126 — Ann Arbor
  • Michigan State University - Site 840-127 — East Lansing
  • Kahana Oculoplastic and Orbital Surgery - Site 840-112 — Livonia

Arizona

  • Catalina Eye Care - Site 840-121 — Tucson

Colorado

  • UC Hospital Sue Anschulz-Rodgers Eye Center - Site 840-101 — Aurora

Kentucky

  • University of Louisville Health Eye Institute - Site 840-108 — Louisville

Massachusetts

  • Ophthalmic Consultants of Boston - Site 840-128 — Boston

Minnesota

  • Mayo Clinic - Site 840-102 — Rochester

Trial Details

FieldValue
Enrollment Target 81 participants
Start Date 2024-02-19
Est. Completion 2027-09
Phase Phase 2

Sponsor

Tourmaline Bio

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06088979

The ClinicalTrials.gov registry entry for NCT06088979 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 81 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Tourmaline Bio, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Thyroid Eye Disease appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06088979 reports 20 study locations spanning 12 distinct geographic areas — top geographies include California, Florida, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06088979 about?

NCT06088979 is a clinical study titled "A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease". Phase 2b trial of TOUR006 in Thyroid Eye Disease (TED) to evaluate 20mg and 50mg doses against placebo given by a subcutaneous injection every eight weeks to TED patients who are in the active inflammatory phase of disease.

What is the current status of trial NCT06088979?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 81 participants. The study started on 2024-02-19. Estimated completion is 2027-09.

What conditions does trial NCT06088979 study?

This clinical trial studies the following conditions: Thyroid Eye Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06088979?

The interventions under investigation include: Placebo (OTHER), TOUR006 - 20 MG (DRUG), TOUR006 - 50 MG (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06088979?

This trial is sponsored by Tourmaline Bio, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06088979 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial