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ClinicalTrials.gov 14 recruiting now official registry

Tetraplegia clinical trials

Every US clinical trial registered for Tetraplegia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

24 US clinical trials · 14 currently recruiting

The research picture

Tetraplegia has 24 registered US clinical trials, 14 of them open to new participants right now — about 58% of the total.

14
recruiting participants now
58%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
4
top sponsor: Leigh R. Hochberg, MD, PhD.

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 40 participants

MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury

Columbia University

NCT05553457

RECRUITING NA 30 participants

Cortical Recording and Stimulating Array Brain-Machine Interface

Michael Boninger

NCT01894802

RECRUITING NA 30 participants

Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury

Kessler Foundation

NCT05432999

RECRUITING 30 participants

Nerve Transfer to Improve Function in High Level Tetraplegia

Washington University School of Medicine

NCT06288763

RECRUITING NA 27 participants

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

Leigh R. Hochberg, MD, PhD.

NCT00912041

RECRUITING NA 12 participants

An Early Feasibility Study of the ReHAB System

Jennifer Sweet, MD

NCT03898804

RECRUITING NA 10 participants

Evaluation of an Advanced Lower Extremity Neuroprostheses

Case Western Reserve University

NCT00623389

RECRUITING 10 participants

Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury

Stanford University

NCT06541041

RECRUITING NA 10 participants

A Neuroprosthesis for Seated Posture and Balance

VA Office of Research and Development

NCT01474148

RECRUITING NA 5 participants

Investigation on the Bidirectional Cortical Neuroprosthetic System

Johns Hopkins University

NCT03161067

RECRUITING NA 3 participants

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

Leigh R. Hochberg, MD, PhD.

NCT05724173

RECRUITING NA 3 participants

Investigation on the Cortical Communication (CortiCom) System

Johns Hopkins University

NCT03567213

RECRUITING NA 2 participants

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)

Leigh R. Hochberg, MD, PhD.

NCT06094205

RECRUITING NA 2 participants

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

Leigh R. Hochberg, MD, PhD.

NCT06511934

ACTIVE NOT RECRUITING 70 participants

Nerve Transfer After Spinal Cord Injury- Multi-center

Washington University School of Medicine

NCT04023591

ACTIVE NOT RECRUITING Phase 1 12 participants

Spinal Cord Neuromodulation for Spinal Cord Injury

University of California, Los Angeles

NCT02313194

ACTIVE NOT RECRUITING NA 10 participants

Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury

MetroHealth Medical Center

NCT00583804

ACTIVE NOT RECRUITING Phase 2 6 participants

Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury

Burke Medical Research Institute

NCT04041063

COMPLETED 31 participants

Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia

Craig Hospital

NCT01815554

COMPLETED Phase 4 30 participants

Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia

James J. Peters Veterans Affairs Medical Center

NCT02379156

COMPLETED NA 26 participants

Spinal Cord Injury Exercise and Nutrition Conceptual Engagement

University of Miami

NCT03495986

COMPLETED NA 20 participants

Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia

US Department of Veterans Affairs

NCT00904436

COMPLETED NA 19 participants

Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function

Shepherd Center, Atlanta GA

NCT04777149

COMPLETED NA 6 participants

Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI

Kristin Zhao, PhD

NCT05095454

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Tetraplegia Trial Landscape

ClinicalTrials.gov lists 24 US studies indexed under Tetraplegia, and 14 of those are currently open to recruitment — roughly 58% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Tetraplegia shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Tetraplegia is led by Leigh R. Hochberg, MD, PhD. with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 24 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Tetraplegia?

PlainTrial tracks 24 US clinical trials for Tetraplegia, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Tetraplegia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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