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ClinicalTrials.gov 14 recruiting now early-phase tilt

Tetraplegia: early-phase trial registry

14 of 24 indexed Tetraplegia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #686 of 28,707 conditions by registered trial count.

24 US clinical trials · 14 currently recruiting · #686 of 28,707 conditions by registered trial count

Tetraplegia: 24 US clinical trials tracked, 14 recruiting.

Tetraplegia is the subject of 24 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Leigh R. Hochberg, MD, PhD., running 4 of these trials.

Enrollment posture brief

Registry condition tetraplegia

OPEN 14 | RECR 58% | LATE 1 | EARLY 2 | RANK #686 | SPON 4

Nearest open-share peer: Anterior Cruciate Ligament Reconstruction (58% recruiting · 12 trials)

Tetraplegia (this)58%Aplastic Anemia37.5%Behavior37.5%Allergic Rhinitis8.3%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Tetraplegia

Tetraplegia lists 14 open slots (58% of 24 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Tetraplegia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Tetraplegia is recruiting above its size-band peers.

    14 of 24 indexed trials (58.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Tetraplegia research.

    Leigh R. Hochberg, MD, PhD. accounts for 4 of 24 trials (16.7%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Most Tetraplegia trials plan to enrol fewer than 100 people.

    Median target enrolment is 12 among the 24 trials that report a genuine target (sentinel values excluded). 24 of those (100%) plan for fewer than 100 participants.

  4. Tetraplegia research is mostly interventional.

    20 interventional and 4 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 21Phase 41

Open and recent trials

24 total, page 1 of 1

RECRUITING NA 40 participants

MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury

Columbia University

NCT05553457

RECRUITING NA 30 participants

Cortical Recording and Stimulating Array Brain-Machine Interface

Michael Boninger

NCT01894802

RECRUITING NA 30 participants

Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury

Kessler Foundation

NCT05432999

RECRUITING 30 participants

Nerve Transfer to Improve Function in High Level Tetraplegia

Washington University School of Medicine

NCT06288763

RECRUITING NA 27 participants

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

Leigh R. Hochberg, MD, PhD.

NCT00912041

RECRUITING NA 12 participants

An Early Feasibility Study of the ReHAB System

Jennifer Sweet, MD

NCT03898804

RECRUITING NA 10 participants

Evaluation of an Advanced Lower Extremity Neuroprostheses

Case Western Reserve University

NCT00623389

RECRUITING 10 participants

Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury

Stanford University

NCT06541041

RECRUITING NA 10 participants

A Neuroprosthesis for Seated Posture and Balance

VA Office of Research and Development

NCT01474148

RECRUITING NA 5 participants

Investigation on the Bidirectional Cortical Neuroprosthetic System

Johns Hopkins University

NCT03161067

RECRUITING NA 3 participants

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

Leigh R. Hochberg, MD, PhD.

NCT05724173

RECRUITING NA 3 participants

Investigation on the Cortical Communication (CortiCom) System

Johns Hopkins University

NCT03567213

RECRUITING NA 2 participants

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)

Leigh R. Hochberg, MD, PhD.

NCT06094205

RECRUITING NA 2 participants

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

Leigh R. Hochberg, MD, PhD.

NCT06511934

ACTIVE NOT RECRUITING 70 participants

Nerve Transfer After Spinal Cord Injury- Multi-center

Washington University School of Medicine

NCT04023591

ACTIVE NOT RECRUITING Phase 1 12 participants

Spinal Cord Neuromodulation for Spinal Cord Injury

University of California, Los Angeles

NCT02313194

ACTIVE NOT RECRUITING NA 10 participants

Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury

MetroHealth Medical Center

NCT00583804

ACTIVE NOT RECRUITING Phase 2 6 participants

Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury

Burke Medical Research Institute

NCT04041063

COMPLETED 31 participants

Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia

Craig Hospital

NCT01815554

COMPLETED Phase 4 30 participants

Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia

James J. Peters Veterans Affairs Medical Center

NCT02379156

COMPLETED NA 26 participants

Spinal Cord Injury Exercise and Nutrition Conceptual Engagement

University of Miami

NCT03495986

COMPLETED NA 20 participants

Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia

US Department of Veterans Affairs

NCT00904436

COMPLETED NA 19 participants

Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function

Shepherd Center, Atlanta GA

NCT04777149

COMPLETED NA 6 participants

Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI

Kristin Zhao, PhD

NCT05095454

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 1
Phase 4 1

Named interventions

Most-linked intervention names on Tetraplegia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

BrainGate Neural Interface System Device
3 trials
Cool Temperature Other
1 trials
Functional Electrical Stimulation Leg Cycle Ergometry Device
1 trials
Transcutaneous electrical spinal stimulation Device
1 trials
Percutaneous epidural electrical spinal stimulation Device
1 trials
ipratropium (Atrovent) Drug
1 trials
sham-stimulation Other
1 trials
transcranial Random Noise Stimulation (tRNS) Other
1 trials

US sites by state

Facility locations filed on Tetraplegia trials. A trial with sites in several states counts in each.

California 7 trials
Ohio 4 trials
New York 4 trials
Pennsylvania 3 trials
Maryland 3 trials
Massachusetts 3 trials
Florida 3 trials
Utah 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Tetraplegia page

24 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Tetraplegia condition card totals 24 registered trials; most-linked intervention BrainGate Neural Interface System; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.