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Tetraplegia clinical trials
Every US clinical trial registered for Tetraplegia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
24 US clinical trials · 14 currently recruiting
The research picture
Tetraplegia has 24 registered US clinical trials, 14 of them open to new participants right now — about 58% of the total.
- 14
- recruiting participants now
- 58%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Leigh R. Hochberg, MD, PhD.
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury
Columbia University
NCT05553457
Cortical Recording and Stimulating Array Brain-Machine Interface
Michael Boninger
NCT01894802
Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury
Kessler Foundation
NCT05432999
Nerve Transfer to Improve Function in High Level Tetraplegia
Washington University School of Medicine
NCT06288763
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia
Leigh R. Hochberg, MD, PhD.
NCT00912041
An Early Feasibility Study of the ReHAB System
Jennifer Sweet, MD
NCT03898804
Evaluation of an Advanced Lower Extremity Neuroprostheses
Case Western Reserve University
NCT00623389
Nerve Transfers Plus Electrical Stimulation to Improve Hand Function in Cervical Spinal Cord Injury
Stanford University
NCT06541041
A Neuroprosthesis for Seated Posture and Balance
VA Office of Research and Development
NCT01474148
Investigation on the Bidirectional Cortical Neuroprosthetic System
Johns Hopkins University
NCT03161067
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia
Leigh R. Hochberg, MD, PhD.
NCT05724173
Investigation on the Cortical Communication (CortiCom) System
Johns Hopkins University
NCT03567213
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)
Leigh R. Hochberg, MD, PhD.
NCT06094205
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)
Leigh R. Hochberg, MD, PhD.
NCT06511934
Nerve Transfer After Spinal Cord Injury- Multi-center
Washington University School of Medicine
NCT04023591
Spinal Cord Neuromodulation for Spinal Cord Injury
University of California, Los Angeles
NCT02313194
Implanted Myoelectric Control for Restoration of Hand Function in Spinal Cord Injury
MetroHealth Medical Center
NCT00583804
Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury
Burke Medical Research Institute
NCT04041063
Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia
Craig Hospital
NCT01815554
Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia
James J. Peters Veterans Affairs Medical Center
NCT02379156
Spinal Cord Injury Exercise and Nutrition Conceptual Engagement
University of Miami
NCT03495986
Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia
US Department of Veterans Affairs
NCT00904436
Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function
Shepherd Center, Atlanta GA
NCT04777149
Short-Term Transcutaneous or Epidural Spinal Stimulation for Enabling Motor Function in Humans With SCI
Kristin Zhao, PhD
NCT05095454
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Tetraplegia Trial Landscape
ClinicalTrials.gov lists 24 US studies indexed under Tetraplegia, and 14 of those are currently open to recruitment — roughly 58% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Tetraplegia shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Tetraplegia is led by Leigh R. Hochberg, MD, PhD. with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 24 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Tetraplegia?
PlainTrial tracks 24 US clinical trials for Tetraplegia, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Tetraplegia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.