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COMPLETED NA

Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function

NCT04777149 · View on ClinicalTrials.gov ↗

Study Summary

Cervical spinal cord injury (SCI) results in hand and arm function impairments and decreased independence in performance of daily activities such as bathing, eating, dressing, writing, or typing. Recent approaches that involve the application of non-invasive brain stimulation have the potential to strengthen the remaining connections between the brain and the spinal cord for improved hand function. Combining brain stimulation with performing upper limb functional tasks may further increase the ability of individuals with tetraplegia to use their hands. The purpose of this study is to investigate if "random noise", a special type of brain stimulation that most people cannot feel, can be used to enhance upper limb function in individuals with spinal cord injury. Specifically, the investigators will examine if a combined treatment protocol of random noise and fine motor training results in greater improvements in motor and sensory hand function compared to fine motor training alone.

Interventions

  • OTHER transcranial Direct Current Stimulation (tDCS)
  • OTHER transcranial Random Noise Stimulation (tRNS)
  • OTHER sham-stimulation

Study Locations (1)

Georgia

  • Shepherd Center — Atlanta

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2021-04-12
Est. Completion 2022-08-10
Phase NA

Sponsor

Shepherd Center, Atlanta GA

8 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04777149

The ClinicalTrials.gov registry entry for NCT04777149 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shepherd Center, Atlanta GA, which has 8 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 3 interventions — of which transcranial Direct Current Stimulation (tDCS) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04777149 reports 1 study location spanning 1 distinct geographic area — top geographies include Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04777149 about?

NCT04777149 is a clinical study titled "Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function". Cervical spinal cord injury (SCI) results in hand and arm function impairments and decreased independence in performance of daily activities such as bathing, eating, dressing, writing, or typing. Recent approaches that involve the application of non-invasive brain stimulation have the potential to s...

What is the current status of trial NCT04777149?

This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2021-04-12. Estimated completion is 2022-08-10.

What conditions does trial NCT04777149 study?

This clinical trial studies the following conditions: Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04777149?

The interventions under investigation include: transcranial Direct Current Stimulation (tDCS) (OTHER), transcranial Random Noise Stimulation (tRNS) (OTHER), sham-stimulation (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04777149?

This trial is sponsored by Shepherd Center, Atlanta GA, which has 8 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04777149 being conducted?

This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial