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NCT04777149 · ClinicalTrials.gov registry record · NA
Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function
A NA study of Spinal Cord Injuries and Tetraplegia, sponsored by Shepherd Center, Atlanta GA.
- Completed
- Registry status
- NA
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT04777149: Completed NA study of Spinal Cord Injuries and Tetraplegia, sponsored by Shepherd Center, Atlanta GA.
NCT04777149 is a NA study of Spinal Cord Injuries and Tetraplegia that has completed, run by Shepherd Center, Atlanta GA. The registered enrollment target is 19 participants, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04777149, a NA study of Spinal Cord Injuries and Tetraplegia, has completed, sponsored by Shepherd Center, Atlanta GA.
- COMPLETED
- Registry status
- NA
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
Cervical spinal cord injury (SCI) results in hand and arm function impairments and decreased independence in performance of daily activities such as bathing, eating, dressing, writing, or typing. Recent approaches that involve the application of non-invasive brain stimulation have the potential to strengthen the remaining connections between the brain and the spinal cord for improved hand function. Combining brain stimulation with performing upper limb functional tasks may further increase the ability of individuals with tetraplegia to use their hands. The purpose of this study is to investigate if "random noise", a special type of brain stimulation that most people cannot feel, can be used to enhance upper limb function in individuals with spinal cord injury. Specifically, the investigators will examine if a combined treatment protocol of random noise and fine motor training results in greater improvements in motor and sensory hand function compared to fine motor training alone.
Primary Outcome
The communication between brain and spinal cord will be evaluated. Sensors that detect muscle activity will be placed over hand muscles. Pulses of stimulation will be applied to the head using a type of non-invasive brain stimulation called transcranial magnetic stimulation (TMS). The size of the muscle response will be recorded.
Conditions Studied
Interventions
- OTHER transcranial Direct Current Stimulation (tDCS)
- OTHER transcranial Random Noise Stimulation (tRNS)
- OTHER sham-stimulation
Study Locations (1)
Georgia
- Shepherd Center - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2021-04-12 |
| Est. Completion | 2022-08-10 |
| Phase | NA |
What the finished NCT04777149 record still lists
NCT04777149 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (69% lower).
The record links to 3 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 3 interventions - of which transcranial Direct Current Stimulation (tDCS) is the first listed.
NCT04777149 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT04777149 about?
NCT04777149 is a clinical study titled "Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function". Cervical spinal cord injury (SCI) results in hand and arm function impairments and decreased independence in performance of daily activities such as bathing, eating, dressing, writing, or typing. Recent approaches that involve the application of non-invasive brain stimulation have the potential to s...
What is the current status of trial NCT04777149?
This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2021-04-12. Estimated completion is 2022-08-10.
What conditions does trial NCT04777149 study?
This clinical trial studies the following conditions: Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury.
What interventions are being tested in trial NCT04777149?
The interventions under investigation include: transcranial Direct Current Stimulation (tDCS) (OTHER), transcranial Random Noise Stimulation (tRNS) (OTHER), sham-stimulation (OTHER).
Who is sponsoring clinical trial NCT04777149?
This trial is sponsored by Shepherd Center, Atlanta GA, which has 17 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04777149 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04777149's enrollment target sits among peer trials
19 138th of 202 higher than 65 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)
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HAPPINESS: cHAnging the Perceived Pain INtEnSity in Populations With Spinal Cord Injury and With Health Disparities: A Feasibility Study
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-
Dosing rTMS for Depression Post-SCI
RECRUITING · NA
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