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NCT00904436 · ClinicalTrials.gov registry record · NA

Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia

A NA study of Tetraplegia and Dyspnea, sponsored by US Department of Veterans Affairs.

Completed
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT00904436 is a NA study of Tetraplegia and Dyspnea that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 20 participants, above the 18-participant average among 23 other Tetraplegia trials with a reported enrollment target (11% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT00904436, a NA study of Tetraplegia and Dyspnea, has completed, sponsored by US Department of Veterans Affairs.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

Breathlessness is an extremely common and uncomfortable symptom that is reported in more than two-thirds of persons with tetraplegia. This disordered pulmonary function is due to respiratory muscle paralysis or to sympathetic denervation results in a restrictive impairment and airway hyperreactivity, respectively. These restrictive and obstructive dysfunctions have been associated with the symptom of breathlessness. However, mechanisms contributing to dyspnea in persons who have tetraplegia are not well understood. It has been demonstrated that persons with tetraplegia have an increased prevalence of breathlessness and may have an altered breathing pattern. The purpose of this study is to determine the breathing pattern at rest and measure the changes in breathing after a bronchodilator treatment (a medicine commonly used to treat asthma that relaxes and opens up airways). The determination of breathing pattern is done by measuring the movements in the chest wall while breathing. This design will elucidate differences in breathing patterns between those with tetraplegia and controls, as well as demonstrate the effect of bronchodilatation on motor drive and timing. Knowledge of the intraindividual variability and mean values of the components of the breathing pattern will improve our understanding of breathlessness in these individuals.

Conditions Studied

Interventions

  • DRUG ipratropium (Atrovent)

Study Locations (1)

New York

  • VA Medical Center, Bronx - The Bronx

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 1999-12
Est. Completion 2001-01
Phase NA

Sponsor

US Department of Veterans Affairs

632 total trials

What the Registry Record Tells You About NCT00904436

The ClinicalTrials.gov registry entry for NCT00904436 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 18-participant average among 23 other Tetraplegia trials with a reported enrollment target (11% higher). The listed sponsor is US Department of Veterans Affairs, which has 632 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Tetraplegia appearing as the primary indexed condition, and to 1 intervention - of which ipratropium (Atrovent) is the first listed.

NCT00904436 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT00904436 about?

NCT00904436 is a clinical study titled "Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia". Breathlessness is an extremely common and uncomfortable symptom that is reported in more than two-thirds of persons with tetraplegia. This disordered pulmonary function is due to respiratory muscle paralysis or to sympathetic denervation results in a restrictive impairment and airway hyperreactivity...

What is the current status of trial NCT00904436?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 1999-12. Estimated completion is 2001-01.

What conditions does trial NCT00904436 study?

This clinical trial studies the following conditions: Tetraplegia, Dyspnea.

What interventions are being tested in trial NCT00904436?

The interventions under investigation include: ipratropium (Atrovent) (DRUG).

Who is sponsoring clinical trial NCT00904436?

This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00904436 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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