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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

T-cell-prolymphocytic Leukemia: early-phase trial registry

5 of 8 indexed T-cell-prolymphocytic Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,176 of 28,707 conditions by registered trial count.

8 US clinical trials · 5 currently recruiting · #2,176 of 28,707 conditions by registered trial count

T-cell-prolymphocytic Leukemia: 8 US clinical trials tracked, 5 recruiting.

T-cell-prolymphocytic Leukemia is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 2 of these trials.

Enrollment posture brief

Registry condition t-cell-prolymphocytic-leukemia

OPEN 5 | RECR 63% | LATE 0 | EARLY 7 | RANK #2176 | SPON 2

Nearest open-share peer: Adolescent (63% recruiting · 16 trials)

Activity, Motor75%T-cell-prolymphocytic Le (th…63%Achalasia50%Abdominal Cancer25%Acne Scars - Mixed Atrophic 25%
Open-enrollment share among volume-matched conditions near T-cell-prolymphocytic Leukemia

T-cell-prolymphocytic Leukemia lists 5 open slots (63% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for T-cell-prolymphocytic Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. T-cell-prolymphocytic Leukemia is recruiting above its size-band peers.

    5 of 8 indexed trials (62.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates T-cell-prolymphocytic Leukemia research.

    Memorial Sloan Kettering Cancer Center accounts for 2 of 8 trials (25%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Most T-cell-prolymphocytic Leukemia trials plan to enrol fewer than 100 people.

    Median target enrolment is 44 among the 8 trials that report a genuine target (sentinel values excluded). 6 of those (75%) plan for fewer than 100 participants.

  4. T-cell-prolymphocytic Leukemia research is mostly interventional.

    7 interventional and 1 observational studies make up this index (87.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 22

Open and recent trials

8 total, page 1 of 1

RECRUITING 1,000 participants

A Registry for People With T-cell Lymphoma

Memorial Sloan Kettering Cancer Center

NCT05978141

RECRUITING Phase 1 100 participants

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

Newave Pharmaceutical

NCT04771572

RECRUITING Phase 1 70 participants

A Study of Ruxolitinib and Duvelisib in People With Lymphoma

Memorial Sloan Kettering Cancer Center

NCT05010005

RECRUITING Phase 2 44 participants

Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma

Jonathan Brammer

NCT07356245

RECRUITING Phase 1 12 participants

Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

Jonsson Comprehensive Cancer Center

NCT06810778

ACTIVE NOT RECRUITING Phase 1 32 participants

Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05823571

ACTIVE NOT RECRUITING Phase 1 6 participants

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

Washington University School of Medicine

NCT05377827

COMPLETED Phase 2 6 participants

Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

Ohio State University Comprehensive Cancer Center

NCT04312841

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 2

Named interventions

Most-linked intervention names on T-cell-prolymphocytic Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Duvelisib Drug
2 trials
Ruxolitinib Drug
2 trials
Positron emission tomography-computed tomography Procedure
1 trials
LP-118 Drug
1 trials
WU-CART-007 Biological
1 trials
Optional Blood Sample and Nail Sample Other
1 trials
Itacitinib Drug
1 trials
Letermovir Drug
1 trials

US sites by state

Facility locations filed on T-cell-prolymphocytic Leukemia trials. A trial with sites in several states counts in each.

Ohio 3 trials
Massachusetts 3 trials
New York 2 trials
New Jersey 2 trials
Missouri 2 trials
Illinois 2 trials
Florida 2 trials
California 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this T-cell-prolymphocytic Leukemia page

8 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This T-cell-prolymphocytic Leukemia condition card totals 8 registered trials; most-linked intervention Duvelisib; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.