Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07104123 · ClinicalTrials.gov registry record · NA
Substance Use in Pregnant People - Optimizing Retention in Treatment
A NA study of Pregnancy and Postpartum, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 2
- Study locations
NCT07104123: Recruiting NA study of Pregnancy and Postpartum, sponsored by Washington University School of Medicine.
NCT07104123 is a NA study of Pregnancy and Postpartum that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 40 participants, below the 872-participant average among 191 other Pregnancy trials with a reported enrollment target (95% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07104123, a NA study of Pregnancy and Postpartum, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 2
- Study locations
Study Summary
Substance use during pregnancy is a leading cause of maternal morbidity and mortality in the United States, with 55-80% of postpartum patients disengaging from substance use disorder (SUD) treatment within one year of delivery. Structural and social determinants of health, including housing instability, transportation barriers, and limited childcare access, further exacerbate disparities in treatment retention. This pilot study, conducted in two specialized prenatal care clinics, evaluates the feasibility and acceptability of two integrated strategies to promote sustained engagement in recovery-oriented services during the perinatal and postpartum periods. Aim 1 implements a standardized social needs screening and referral protocol to connect patients with community-based supports. Aim 2 pilots a contingency management intervention to incentivize recovery-supportive behaviors. Findings will inform the design of a larger multi-site randomized controlled trial to evaluate the impact of these interventions on treatment retention, overdose prevention, and maternal-infant health outcomes.
Primary Outcome
Percentage of eligible patients enrolled in the study
Conditions Studied
Interventions
- OTHER Social drivers of health screening
- BEHAVIORAL Patients will undergo a program of contingency management
Study Locations (2)
Maryland
- University of Maryland - Baltimore
Missouri
- Washington University - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-02-02 |
| Est. Completion | 2026-08 |
| Phase | NA |
What NCT07104123 shows while recruiting
NCT07104123 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 872-participant average among 191 other Pregnancy trials with a reported enrollment target (95% lower).
The record links to 4 conditions, with Pregnancy appearing as the primary indexed condition, and to 2 interventions - of which Social drivers of health screening is the first listed.
NCT07104123 reports a single indexed study location in Maryland, Missouri.
Frequently Asked Questions
What is clinical trial NCT07104123 about?
NCT07104123 is a clinical study titled "Substance Use in Pregnant People - Optimizing Retention in Treatment". Substance use during pregnancy is a leading cause of maternal morbidity and mortality in the United States, with 55-80% of postpartum patients disengaging from substance use disorder (SUD) treatment within one year of delivery. Structural and social determinants of health, including housing instabil...
What is the current status of trial NCT07104123?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2026-02-02. Estimated completion is 2026-08.
What conditions does trial NCT07104123 study?
This clinical trial studies the following conditions: Pregnancy, Postpartum, Substance Use Disorder (SUD), Contingency Management.
What interventions are being tested in trial NCT07104123?
The interventions under investigation include: Social drivers of health screening (OTHER), Patients will undergo a program of contingency management (BEHAVIORAL).
Who is sponsoring clinical trial NCT07104123?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07104123 being conducted?
This trial has 2 study locations across Maryland, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pregnancy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07104123's enrollment target sits among peer trials
40 162nd of 191 higher than 27 of 191 other Pregnancy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pregnancy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes
RECRUITING · NA
-
Cocooned Moms Study
RECRUITING · NA
-
CGM for Management of Type 2 Diabetes in Pregnancy
RECRUITING · NA
-
Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health
RECRUITING · NA
-
Enhancing Care & Outcomes for Patients During the First Postpartum Year
RECRUITING · NA
-
Mitigating Response to Stressors in Pregnant Women
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI