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NCT07433985 · ClinicalTrials.gov registry record · NA
California MEPS Hub
A NA study of HIV Prevention and Substance Use Disorder (SUD), sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 318
- Enrollment target
- 3
- Study locations
NCT07433985 is a NA study of HIV Prevention and Substance Use Disorder (SUD) that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 318 participants, below the 372-participant average among 32 other HIV Prevention trials with a reported enrollment target (15% lower). The trial reports 3 study locations across 1 state.
The verdict
NCT07433985, a NA study of HIV Prevention and Substance Use Disorder (SUD), is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 318 participants
- Enrollment target
- 3
- Study locations
Study Summary
The California Hub for HIV/SUD Prevention Research with Reentry Populations addresses the question: "Can the evidence-based MEPS intervention be adapted and implemented at a range of organizations to effectively serve a wider range of clients?" The Mobile Enhanced Prevention Support (MEPS) intervention was originally implemented in Los Angeles County and was proven successful in promoting biomedical HIV prevention (PrEP) uptake and preventative screenings in people who used drugs who recently left incarceration. MEPS is an evidence-based intervention for people with substance use disorders (SUD) that incorporates a client-centered planning session, including trained peer mentors, service utilization incentives, and a mobile application (GeoPass). The study includes a randomized controlled trial (RCT) across three community partners located in Riverside and Alameda Counties. At least 300 people will be enrolled in these three counties; the first 200 will be randomized to either receive the intervention or usual care, with the final 100 all receiving the intervention. The primary implementation outcome for the study involves using an implementation science framework and assessment tools to examine MEPS's implementation. Key outcomes include how well the implementation strategies used support intervention enrollment and retention, integration with existing services in each partnering community agency, and perceived intervention acceptability, feasibility, appropriateness, and maintenance at 6- and 12-months. The primary effectiveness outcome for the study is an increase in HIV testing, PrEP uptake and adherence, and SUD service utilization at 6 months and 12 months in the MEPS compared to the usual care group. Secondary effectiveness outcomes include frequency of service use for SUDs, hepatitis C virus testing, and linkage to care for those who test positive for HIV or hepatitis C.
Conditions Studied
Interventions
- OTHER Control
- BEHAVIORAL Mobile Enhanced Prevention Support (MEPS)
Study Locations (3)
California
- CAL-PEP - Oakland
- Kindful Restoration - Riverside
- Starting Over, Inc - Riverside
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 318 participants |
| Start Date | 2025-12-01 |
| Est. Completion | 2029-07-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07433985
The ClinicalTrials.gov registry entry for NCT07433985 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 318 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 372-participant average among 32 other HIV Prevention trials with a reported enrollment target (15% lower). The listed sponsor is University of California, Los Angeles, which has 897 total studies on file at ClinicalTrials.gov.
The record links to 6 conditions, with HIV Prevention appearing as the primary indexed condition, and to 2 interventions - of which Control is the first listed.
NCT07433985 reports 3 study locations spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT07433985 about?
NCT07433985 is a clinical study titled "California MEPS Hub". The California Hub for HIV/SUD Prevention Research with Reentry Populations addresses the question: "Can the evidence-based MEPS intervention be adapted and implemented at a range of organizations to effectively serve a wider range of clients?" The Mobile Enhanced Prevention Support (MEPS) interven...
What is the current status of trial NCT07433985?
This trial is currently recruiting. It is a NA study. The enrollment target is 318 participants. The study started on 2025-12-01. Estimated completion is 2029-07-31.
What conditions does trial NCT07433985 study?
This clinical trial studies the following conditions: HIV Prevention, Substance Use Disorder (SUD), Incarceration, Sexually Transmitted Infections (STI), Preexposure Prophylaxis (PrEP).
What interventions are being tested in trial NCT07433985?
The interventions under investigation include: Control (OTHER), Mobile Enhanced Prevention Support (MEPS) (BEHAVIORAL).
Who is sponsoring clinical trial NCT07433985?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07433985 being conducted?
This trial has 3 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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