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NCT05489146 · ClinicalTrials.gov registry record · NA
t-RNS After Hand Recovery in Chronic Stroke
A NA study of Stroke, sponsored by Amit Sethi.
- Completed
- Registry status
- NA
- Development phase
- 14
- Enrollment target
- 1
- Study location
NCT05489146: Completed NA study of Stroke, sponsored by Amit Sethi.
NCT05489146 is a NA study of Stroke that has completed, run by Amit Sethi. The registered enrollment target is 14 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05489146, a NA study of Stroke, has completed, sponsored by Amit Sethi.
- COMPLETED
- Registry status
- NA
- Development phase
- 14 participants
- Enrollment target
- 1
- Study location
Study Summary
Upper extremity (UE) paresis or weakness is one of the most frequent impairments after stroke. Despite intense rehabilitation, motor and functional recovery of patients with severe hand impairments is poor. Hence, there is a need for more effective treatments to enhance motor function in patients with severe hand impairments after stroke. Adaptive functional electrical stimulation (FES) appears to be a promising treatment and has the potential to facilitate active movement in individuals with severe impairments post-stroke. In addition, transcranial random noise stimulation (trns) is a widely studied, non-invasive and safe method to enhance the corticomotor excitability in individuals with chronic stroke. However, the effect of combining trns and adaptive FES in patients with severe hand impairments has not been investigated. Therefore, the purpose of this study is to investigate whether combining trns with FES will enhance hand function in individuals with chronic stroke than FES alone. The investigators predict that combining trns with FES will significantly enhance hand function than FES alone.
Primary Outcome
Fugl Meyer Upper Extremity Scale (FMUE) is considered the gold standard in upper extremity rehabilitation trials and measures upper extremity motor control by asking the participant to perform various arm and hand motions. Items are scored on a 3-point ordinal scale with 0 representing inability to complete the item and 2 representing the ability to complete the item as asked. We will use the total score, which ranges from 0-66. Higher score suggest better upper extremity motor control. The FMUE
Conditions Studied
Interventions
- DEVICE transcranial random noise stimulation and functional electrical stimulation facilitated task practice
Study Locations (1)
Pennsylvania
- Neuromotor Recovery and Rehabilitation Lab - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2015-01-15 |
| Est. Completion | 2020-03-15 |
| Phase | NA |
What the finished NCT05489146 record still lists
NCT05489146 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which transcranial random noise stimulation and functional electrical stimulation facilitated task practice is the first listed.
NCT05489146 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05489146 about?
NCT05489146 is a clinical study titled "t-RNS After Hand Recovery in Chronic Stroke". Upper extremity (UE) paresis or weakness is one of the most frequent impairments after stroke. Despite intense rehabilitation, motor and functional recovery of patients with severe hand impairments is poor. Hence, there is a need for more effective treatments to enhance motor function in patients wi...
What is the current status of trial NCT05489146?
This trial is currently completed. It is a NA study. The enrollment target is 14 participants. The study started on 2015-01-15. Estimated completion is 2020-03-15.
What conditions does trial NCT05489146 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT05489146?
The interventions under investigation include: transcranial random noise stimulation and functional electrical stimulation facilitated task practice (DEVICE).
Who is sponsoring clinical trial NCT05489146?
This trial is sponsored by Amit Sethi, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05489146 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05489146's enrollment target sits among peer trials
14 400th of 454 higher than 54 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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