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ClinicalTrials.gov official registry

Stage IIIC Cutaneous Melanoma AJCC v7 clinical trials

All 13 indexed Stage IIIC Cutaneous Melanoma AJCC v7 trials have closed enrollment.

13 US clinical trials ·

Stage IIIC Cutaneous Melanoma AJCC v7 is the subject of 13 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 1 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 7 of these trials.

The research picture

Stage IIIC Cutaneous Melanoma AJCC v7 has 13 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
7
top sponsor: National Cancer Institute (NCI)
Phase 14Phase 28Phase 31

Active & Recent Trials

13 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 3 1,673 participants

Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery

National Cancer Institute (NCI)

NCT01274338

ACTIVE NOT RECRUITING Phase 2 245 participants

Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT01134614

ACTIVE NOT RECRUITING Phase 2 88 participants

Ipilimumab With or Without High-Dose Recombinant Interferon Alfa-2b in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT01708941

ACTIVE NOT RECRUITING Phase 1 62 participants

Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer

National Cancer Institute (NCI)

NCT01480154

ACTIVE NOT RECRUITING Phase 2 58 participants

Dabrafenib and Trametinib Before and After Surgery in Treating Patients With Stage IIIB-C Melanoma With BRAF V600 Mutation

M.D. Anderson Cancer Center

NCT02231775

ACTIVE NOT RECRUITING Phase 2 52 participants

Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma

M.D. Anderson Cancer Center

NCT02910700

ACTIVE NOT RECRUITING Phase 2 43 participants

Talimogene Laherparepvec and Pembrolizumab in Treating Patients With Stage III-IV Melanoma

National Cancer Institute (NCI)

NCT02965716

ACTIVE NOT RECRUITING Phase 1 35 participants

Riluzole and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors or Melanoma

National Cancer Institute (NCI)

NCT01303341

ACTIVE NOT RECRUITING Phase 1 34 participants

Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma

M.D. Anderson Cancer Center

NCT01955460

ACTIVE NOT RECRUITING Phase 1 20 participants

Pembrolizumab and Ibrutinib in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Mayo Clinic

NCT03021460

COMPLETED Phase 2 169 participants

Ipilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT01950390

COMPLETED Phase 2 18 participants

Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma

M.D. Anderson Cancer Center

NCT02500576

COMPLETED Phase 2 11 participants

Tumor-Infiltrating Lymphocytes After Combination Chemotherapy in Treating Patients With Metastatic Melanoma

Fred Hutchinson Cancer Center

NCT01807182

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 8
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Stage IIIC Cutaneous Melanoma AJCC v7 Trial Landscape

13 indexed Stage IIIC Cutaneous Melanoma AJCC v7 studies · 0 recruiting (0%).

Phase mix: 1 late (III/IV) vs 12 early (I/II).

Top sponsor: National Cancer Institute (NCI) (7 trials), 3 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Stage IIIC Cutaneous Melanoma AJCC v7?

PlainTrial tracks 13 US clinical trials for Stage IIIC Cutaneous Melanoma AJCC v7, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stage IIIC Cutaneous Melanoma AJCC v7?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.